播散性浅表性光线性汗孔角化症并发寻常型银屑病1例  

A case of disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris

作　　者：马铜川 董丽萍 肖风丽[1,2,3] MA Tongchuan;DONG Liping;XIAO Fengli(First Affiliated Hospital,Institute of Dermatology,Anhui Medical University,Hefei 230032,China;Key Laboratory of Dermatology,Anhui Medical University,Ministry of Education,Hefei 230032,China;First Affiliated Hospital,Laboratory of Inflammatory and Immune Diseases,Hefei 230032,China)

机构地区：[1]安徽医科大学第一附属医院,安徽医科大学皮肤病研究所,安徽合肥230032 [2]安徽医科大学第一附属医院,安徽医科大学皮肤病学教育部重点实验室,安徽合肥230032 [3]安徽医科大学第一附属医院,安徽省炎症与免疫性疾病实验室,安徽合肥230032

出　　处：《皮肤性病诊疗学杂志》2025年第3期211-214,共4页Journal of Diagnosis and Therapy on Dermato-venereology

基　　金：国家自然科学基金(82373481);安徽省高校自然科学基金重点项目(2023AH053302)。

摘　　要：报告1例播散性浅表性光线性汗孔角化症并发寻常型银屑病。患者女,57岁。因全身散在皮疹50年,近4个月出现新发皮疹就诊。皮肤科检查:四肢散在红色斑块,边界清楚,其上可见银白色鳞屑,刮之可见薄膜现象及点状出血;四肢、面部可见散在褐色环形皮损,边缘稍隆起、中间轻微凹陷。红斑鳞屑皮损组织病理:表皮角化过度及角化不全,棘层增厚,表皮突延长,真皮乳头血管扩张,浅层小血管增生伴炎细胞浸润;褐色环形皮损组织病理:表皮角化过度,表皮凹窝可见角化不全柱。诊断:播散性浅表性光线性汗孔角化症并发寻常型银屑病。予口服复方甘草酸苷片、外用卡泊三醇乳膏。患者失访。We report a case of disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris.A 57-year-old female presented with scattered rashes across her body for 50 years,and new rashes for 4 months.Dermatologic examination revealed scattered red plaques and silvery scales on the limbs with clear boundaries and Auspitz's sign.Scattered brown annular lesions with slightly elevated margins and slight depression in the center were seen on the extremities and face.Histopathology of erythematous scaly lesions on the lateral aspect of the left calf showed epidermal hyperkeratosis and parakeratosis,Munro microabscesses,thickening of the stratum spinosum,elongation of rete ridges,vasodilation,and small vessel hyperplasia with inflammatory cell infiltration in the dermis.Histopathology of brown annular lesions on the lateral aspect of the left calf showed epidermal hyperkeratosis and parakeratotic plugs.Diagnosis:disseminated superficial actinic porokeratosis complicated with psoriasis vulgaris.Oral compound glycyrrhizin tablets and topical calcipotriol ointment were administered,and the patient was lost to follow-up.

关 键 词：汗孔角化症 银屑病 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]