出 处:《中国民康医学》2025年第8期68-71,共4页Medical Journal of Chinese People’s Health
摘 要:目的:观察腹腔镜疝囊高位结扎术治疗腹股沟疝患儿的效果。方法:回顾性分析2020年8月至2024年8月该院收治的283例腹股沟疝患儿的临床资料,按手术方式不同将其分为对照组141例与观察组142例。对照组采用传统开放式疝囊高位结扎术治疗,观察组采用腹腔镜疝囊高位结扎术治疗,比较两组手术相关指标(术中出血量、手术时间、首次下床活动时间、住院时间)水平、术后疼痛程度[视觉模拟评分法(VAS)]评分、炎性因子[白细胞计数(WBC)、白细胞介素-10(IL-10)、C反应蛋白(CRP)、白细胞介素-6(IL-6)]水平、应激反应指标[谷胱甘肽过氧化物酶(GSH-Px)、皮质醇(Cor)、丙二醛(MDA)、去甲肾上腺素(NE)]水平和并发症发生率。结果:观察组术中出血量少于对照组,手术时间、首次下床活动时间、住院时间均短于对照组,差异有统计学意义(P<0.05);术后12、24 h,两组VAS评分均低于术后6 h,且观察组低于对照组,差异有统计学意义(P<0.05);术后1 d,两组WBC、IL-10、CRP、IL-6水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);术后1 d,两组GSH-Px水平均低于术前,但观察组高于对照组,两组Cor、MDA、NE水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为3.52%(5/142),低于对照组的15.60%(22/141),差异有统计学意义(P<0.05)。结论:腹腔镜疝囊高位结扎术治疗腹股沟疝患儿可降低疼痛程度评分、炎性因子水平和并发症发生率,以及改善应激反应指标与手术相关指标水平的效果优于传统开放式疝囊高位结扎术治疗。Objective:To observe effects of laparoscopic high ligation of hernia sac in treatment of children with inguinal hernia.Methods:The clinical data of 283 children with inguinal hernia admitted to this hospital from August 2020 to August 2024 were retrospectively analyzed.According to different surgical methods,they were divided into control group(141 cases)and observation group(142 cases).The control group was treated with traditional open high ligation of hernia sac,while the observation group was treated with laparoscopic high ligation of hernia sac.The levels of operation-related indexes(intraoperative blood loss,operation time,first out-of-bed time,hospitalization time),the postoperative pain degree[visual analogue scale(VAS)]score,the inflammatory factors[white blood cell count(WBC),interleukin-10(IL-10),C-reactive protein(CRP),interleukin-6(IL-6)]levels,the stress indexes[glutathione peroxidase(GSH-Px),cortisol(Cor),malondialdehyde(MDA),norepinephrine(NE)]levels,and the incidence of complications were compared between the two groups.Results:The intraoperative blood loss in the observation group was less than that in the control group,the operation time,the first out-of-bed time and the hospitalization time were shorter than those in the control group,and the differences were statistically significant(P<0.05).12 and 24 h after the surgery,the VAS scores of the two groups were lower than those 6 h after the surgery,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).1 day after the surgery,the levels of WBC,IL-10,CRP and IL-6 in the two groups were higher than those before the surgery,but those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).1 day after the surgery,the levels of GSH-Px in the two groups were lower than those before the surgery,but that in the observation group was higher than that in the control group;the levels of Cor,MDA and NE in the
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