基于纳米酶的比色传感器检测重金属的研究进展  

Research Progress of Colorimetric Sensors Based on Nanoenzymes for Detection of Heavy Metals

作　　者：黄晓婧 张雪晴 刘娅楠 周芷任 邹立娜 潘洪志 荣胜忠 马宏坤 HUANG Xiaojing;ZHANG Xueqing;LIU Yanan;ZHOU Zhiren;ZOU Lina;PAN Hongzhi;RONG Shengzhong;MA Hongkun(Public Health School,Mudanjiang Medical University,Mudanjiang 157011,China;Hongqi Hospital Affiliated to Mudanjiang Medical University,Mudanjiang 157011,China;Collaborative Research Center,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China)

机构地区：[1]牡丹江医科大学公共卫生学院,牡丹江157011 [2]牡丹江医科大学附属红旗医院,牡丹江157011 [3]上海健康医学院协同科研中心,上海201318

出　　处：《理化检验(化学分册)》2025年第4期489-496,共8页Physical Testing and Chemical Analysis(Part B:Chemical Analysis)

基　　金：国家自然科学基金(82173568,81703269,82273687);春雁支持计划青年英才团队项目(CYQN24028);黑龙江省自然科学基金(LH2023H054);黑龙江省医药卫生科研课题(20221212060609);牡丹江市应用技术研究与开发计划项目(HT2022NS113);牡丹江医学院研究生导师科研专项计划项目(YJSZX2022137);牡丹江医学院火炬计划项目(2022-MYHJ-014)。

摘　　要：重金属污染严重威胁人体健康和生态系统安全,实现简便、快速地检测重金属,是有效监测污染状况的关键。与天然酶相比,纳米酶具有活性稳定、成本低等优点。基于纳米酶构建的比色传感器已引起诸多学者的广泛关注,逐渐成为检测重金属的常用方法之一。为此,简要概述了比色传感器的原理、比色方法和纳米酶材料分类及其类酶活性,重点综述了纳米酶比色传感器在重金属检测领域的研究进展,并展望了其实际应用中所面临的挑战与未来的发展方向(引用文献70篇)。Heavy metal pollution poses a serious threat to human health and ecosystem security,and achieving simple and rapid detection of heavy metals is the key to effectively monitoring the pollution situation.Compared with natural enzymes,nanoenzymes have advantages such as stable activity and low cost.Colorimetric sensors based on nanoenzymes have attracted widespread attention from many scholars and have gradually become one of the common methods for the detection of heavy metals.Therefore,the principle and colorimetric methods of colorimetric sensors,classification of nanoenzyme materials and their enzyme-like activities were briefly summarized.The research progress of nanoenzyme colorimetric sensors for heavy metal detection was reviewed,and challenges faced and future development directions in their practical applications were also presented(70 ref.cited).

关 键 词：纳米酶 比色传感器 重金属 

分 类 号：O65[理学—分析化学]