冠状动脉周围脂肪CT脂肪衰减指数与冠脉粥样硬化、斑块性质的关系  

Relationship of CT fat attenuation index of pericoronary adipose tissue with coronary atherosclerosis and plaque properties

作　　者：涂波 肖维良 潘志华 刘冬梅 李健 肖科 刘嘉 李虹成 赵德春 谢红英 TU Bo;XIAO Weiliang;PAN Zhihua;LIU Dongmei;LI Jian;XIAO Ke;LIU Jia;LI Hongcheng;ZHAO Dechun;XIE Hongying(Department of Radiology,The Second Affiliated Hospital of Chengdu Medical College·Nuclear Industry 416 Hospital,Chengdu 610051,China)

机构地区：[1]成都医学院第二附属医院·核工业四一六医院放射科,四川成都610051

出　　处：《分子影像学杂志》2025年第4期474-478,共5页Journal of Molecular Imaging

基　　金：四川省科技厅科研课题(21YYJC0960)。

摘　　要：目的探讨冠状动脉周围脂肪(PCAT)CT脂肪衰减指数(FAI)与冠脉粥样硬化、斑块性质的关系。方法回顾性分析2022年1月~2024年12月于本院行冠状动脉CT血管造影(CTA)检查的138例患者,测量所有患者PCAT的FAI值,并分析其与冠脉粥样硬化程度、斑块性质的关系。结果138例患者中病灶共206个。PCAT的FAI值与冠状动脉狭窄程度和斑块性质有一定的关系,轻、中、重度冠状动脉狭窄斑块的FAI值高于轻微狭窄,非钙化斑块、混合斑块的FAI值高于钙化斑块,非钙化斑块的FAI值高于混合斑块,差异均有统计学意义(P<0.05)。多元线性回归结果显示,FAI值与斑块性质呈正相关关系(P<0.05)。结论PCAT的FAI值与冠脉粥样硬化、斑块性质有一定的关联,不稳定的炎症高风险斑块周围脂肪FAI值的测量有助于临床评估患者冠心病风险。Objective To explore the relationship between CT fat attenuation index(FAI)of pericoronary adipose tissue(PCAT)and coronary atherosclerosis,plaque properties.Methods A total of 138 patients undergoing coronary CT angiography(CTA)in the hospital from January 2022 to December 2024 were retrospectively analyzed.FAI value of PCAT in all patients was measured to analyze its relationship with coronary atherosclerosis and plaque properties.Results There were 206 lesions in all the 138 patients.FAI value of PCAT has certain relationship with coronary stenosis and plaque properties.FAI value in plaques with mild,moderate and severe coronary stenosis was greater than that with slight stenosis,and which was gradually decreased in non-calcification plaques,mixed plaques and calcification plaques(P<0.05).The results of multiple linear regression analysis showed that FAI value was positively correlated with plaque properties(P<0.05).Conclusion FAI value of PCAT has certain correlation with coronary atherosclerosis and plaque properties.Measuring FAI value around plaques with high risk of unstable inflammation is beneficial to clinically evaluate the risk of coronary heart disease.

关 键 词：冠状动脉粥样硬化 CT血管造影 冠状动脉周围脂肪 脂肪衰减指数 斑块性质 

分 类 号：R541.4[医药卫生—心血管疾病]