子宫腺肌病术前免疫炎症指数与高强度聚焦超声术后复发的关系研究  

Study on the Relationship between Preoperative Immune Inflammatory Index and Postoperative Recurrence of Adenomyosis

作　　者：陈荣荣 徐经安 王俊华 Chen Rongrong;Xu Jingan;Wang Junhua(Department of Obstetrics and Gynecology,Anyang Maternal and Child Health Hospital,Anyang,Henan 455000,China)

机构地区：[1]安阳市妇幼保健院妇产科,河南安阳455000

出　　处：《哈尔滨医药》2025年第2期21-25,共5页Harbin Medical Journal

摘　　要：目的探究子宫腺肌病患者术前免疫炎症指数(SII)与高强度聚焦超声(HIFU)术后复发的关系。方法随机抽取120例子宫腺肌病患者作为调查对象,根据复发情况将其分为复发组(21例)和未复发组(99例)。Kaplan-Meier法进行绘制其复发曲线;比较术后1年内复发组与未复发组临床资料;二元logistic回归分析患者术后1年内复发的危险因素;Pearson、Kendall分析术前SII与术后1年内复发独立影响因素的关系。结果120例患者均完成了随访,术后1年内复发21例,复发率为17.50%;人口学资料比较发现,复发组与未复发组年龄、子宫体积、宫腔操作数、病灶类型、消融率、术前SII比较差异有统计学意义(P<0.05);多因素logistic回归分析结果显示,年龄≥35岁、术前子宫体积≥200cm^(3)、术前病灶类型为弥漫型、术前SII、术前宫腔操作数为影响患者术后1年内复发的独立危险因素(OR=27.424、11.976、39.553、1.110、11.357,P<0.05),高消融率为术后1年内复发的保护因素(OR=0.016,P<0.05);Pearson、Kendall分析发现,术前SII与年龄、术前子宫体积、消融率呈正相关关系;而与术前病灶类型、术前宫腔操作数无相关关系。结论多因素logistic回归分析显示年龄≥35岁、术前子宫体积≥200cm^(3)、术前病灶类型为弥漫型、术前SII以及术前宫腔操作数是影响患者术后复发的独立危险因素,而高消融率则是保护因素,并且术前SII与年龄、术前子宫体积、消融率呈正相关关系,因此术前SII可作为预测子宫腺肌病HIFU术后复发的重要指标之一。Objective To explore the relationship between preoperative immune inflammatory index(SII)and postoperative recurrence of high intensity focused ultrasound(HIFU)in patients with adenomyosis.Methods 120 patients with adenomyosis who underwent physical examination were randomLy selected and divided into relapse group(21 cases)and non-relapse group(99 cases)according to the recurrence situation.Kaplan-Meier method was used to draw the recurrence curve.The clinical data of recurrent group and non-recurrent group within 1 year after operation were compared.The risk factors of recurrence within one year after operation were analyzed by binary logistic regression.Pearson and Kendall analyzed the relationship between preoperative SII and independent influencing factors of recurrence within one year after operation.Results All the 120 patients were followed up,and 21 cases recurred within one year after operation,with a recurrence rate of 17.50%.The comparison of demographic data showed that there were significant differences in age,uterine volume,uterine cavity operation number,lesion type,ablation rate and preoperative SII between recurrent group and non-recurrent group(P<0.05).Multivariate logistic regression analysis showed that age≥35,preoperative uterine volume≥200,preoperative focus type,high preoperative SII and high preoperative uterine cavity operation were independent risk factors for recurrence within one year after operation(OR=27.424,11.976,39.553,1.110,11.357,P<0.05).Pearson and Kendall analysis showed that preoperative SII was positively correlated with age,preoperative uterine volume and ablation rate(P<0.05).However,there was no correlation with preoperative lesion type and preoperative uterine cavity operation(P>0.05).Conclusion Multivariate logistic regression analysis shows that age≥35 years old,preoperative uterine volume≥200 cm,preoperative focus type,high preoperative SII and high preoperative uterine cavity operation number are independent risk factors affecting postoperative recurrence,whi

关 键 词：子宫腺肌病 术前 免疫炎症指数 高强度聚焦超声术 复发 

分 类 号：R711.74[医药卫生—妇产科学]