肌腱修复中防治粘连的研究进展  

Research Progress of Preventing Adhesion in Tendon Repair

作　　者：胡伟珍 于昕仪 姜锦珊 王淑芳[1] HU Wei-zhen;YU Xin-yi;JIANG Jin-shan;WANG Shu-fang(Key Laboratory of Bioactive Materials of Ministry of Education,School of Life Sciences,Nankai University,Tianjin 300071,China)

机构地区：[1]南开大学生命科学学院,生物活性材料教育部重点实验室,天津300071

出　　处：《离子交换与吸附》2025年第2期129-141,I0002,共14页Ion Exchange and Adsorption

基　　金：京津冀基础研究合作专项(基金号22JCZXJC00080);天津市自然科学基金重点项目(基金号S22ZDF291)。

摘　　要：肌腱损伤会严重影响人们的生活质量,而肌腱修复过程中常会引发肌腱粘连这一并发症,且目前并无有效的治疗方案。目前的防治方法大多以口服药和手术为主。研究发现,炎症反应、细胞行为、生长因子等都会影响肌腱粘连的形成。近年来,随着对肌腱愈合机制研究的不断深入以及材料科学的发展,肌腱损伤修复及肌腱粘连防治取得重大进展。文章介绍了肌腱愈合的过程,讨论了目前肌腱修复过程中防治肌腱粘连的各种手段,以期为临床防治提供参考。Tendon injury seriously affects people's live quality, and tendon adhesion often exists after tendon repair, and there is no effective treatment plan at present. Most of the prevention and treatment methods are mainly oral drugs and surgery. The study found that inflammatory reactions, cell behavior and growth factors can cause tendon adhesion. In recent years, with the corresponding research on the mechanism of tendon healing and the development of material science, significant progress has been made in the repair of tendon injury and the prevention and treatment of tendon adhesion. This article introduces the process of tendon healing and discusses various therapeutic treatment methods to prevent tendon adhesion in the repair process, so as to provide references for clinical prevention and treatment for tendon injury.

关 键 词：肌腱修复 肌腱粘连 炎症反应 组织工程 

分 类 号：R686[医药卫生—骨科学]