215例正常新生儿瞬态诱发耳声发射测试分析及随访研究  

Measurement of transient evoked otoacoustic emissions and follow-up of 215 healthy newborns

作　　者：于红[1] 余力生[1] 李蔷[1] 丁元吉 马鑫[1] 丁国玉[1] 

机构地区：[1]北京大学人民医院耳鼻咽喉科,北京100044 [2]河北省定州市105医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉科杂志》2003年第1期22-24,共3页Journal of Clinical Otorhinolaryngology

摘　　要：目的 :进一步了解正常新生儿瞬态诱发耳声发射 (TEOAE)的特性 ,为新生儿听力筛查提供帮助。方法 :采用ILO96型耳声发射仪 ,对出生后 0 (出生当天 )～ 8d的 2 15例 (42 5耳 )正常新生儿进行TEOAE测试 ,并跟踪随访。结果 :TEOAE总检出率为 89% ,检出率与检测时的天龄有一定的关系 ,新生儿出生后 0～ 3d检出率平均为 72 % ,4～ 8d为 97%。分娩方式、左右耳、孕龄 36至 4 1周间的差异对检出率无明显影响 ;女性的检出率显著高于男性。快速扫描较TEOAE测试敏感。经随访确诊有 1耳听力损害。结论 :新生儿听力筛查应在出生后≥ 4d出院前进行 ;分娩方式对耳蜗功能无明显影响 ;人耳蜗毛细胞的成熟是在怀孕 36周以前 ;快速扫描不能代替TEOAE测试 ;对于 1耳或双耳未检出TEOAE的受测者必须跟踪随访和复检 ,并结合ABR测试尽早确诊。Objective:To evaluate the characteristics of transient evoked otoacoustic emissions (TEOAE) of healthy newborns and improve hearing screening of newborns.Method:To investigate the history of pregnancy and parturition, TEOAE was measured in 425 ears of 215 healthy newborns from 0 to 8 days postpartum and follow up study was undertaken.Result:The general prevalence was 89%. There was some relationship between prevalence and testing time. The average prevalence was 74% in newborns of 0～3 days. The prevalence was 97% in newborns of 4～8 days. The way of parturition, laterality and time of pregnancy over 36 weeks hadn't any significant effect on the prevalence rate. The prevalence of females was higher than males. Quick screen was more sensitive than TEOAE. One ear of hearing loss was diagnosed after follow up.Conclusion:The hearing screening test of newborns should be taken in hospitals after 4 days of birth, the way of parturition had no effect on the cochlear function. The mature time of cochlear hair cells was by the 36th week of pregnancy. Quick screen couldn't take place of TEOAE. Someone who had no TEOAE in one ear or two ears must be followed up and reexamined and exact diagnosis could be made as soon as possible combining with ABR.

关 键 词：瞬态诱发耳声发射 新生儿 听力筛查 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]