化学消融术治疗肥厚梗阻型心肌病  

The effect of percutaneous transluminal septal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy

作　　者：黄俊[1] 马业新[1] 邱旭光[1] 肖建民[1] 罗惠珍[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院心内科,430030

出　　处：《临床内科杂志》2003年第1期18-20,共3页Journal of Clinical Internal Medicine

摘　　要：目的　探讨经皮室间隔心肌消融术 (PTSMA)治疗肥厚梗阻型心肌病 (HOCM )的可行型、安全型及近中期效果。方法　选择 5例药物治疗效果不佳的HOCM患者 ,经冠脉间隔支造影后球囊试堵靶血管、左心室流出道压力阶差 (LVOTG )监测 ,无水酒精消融靶间隔支。结果　 5例PTSMA手术成功率 10 0 %,术后即刻LVOTG下降 5 0 %～ 88%,未发生严重心律失常 ,术后及随访 (平均随访 11.5 4个月 )临床症状缓解明显 ,运动耐量显著提高。结论　PTSMA是治疗HOCM有效的非外科手段。Objective To evaluate the immediate and follow-up results of percutaneous transluminal septal myocardial ablation(PTSMA) in patients with hypertrophic obstructive cardiomyopathy(HOCM).Methods 5 patients with HOCM refractory to medication was included. Selected septal branch angiography was taken. The methods of target septal branch selection included balloon occlusion test and left ventricular outflow tract pressure gradient(LVOTG) monitor. Alcohol was injected into the target septal branch.Results The successful rate of PTSMA operation was 100%. Tested by catheter, LVOTG reduced 50%～88%. No severe arrhythmia occurred. During a mean of 11.54 months follow-up, the clinical symptom and exercise endurance of patients were improved.Conclution PTSMA is a effectively non-surgical trentment method for HOCM.

关 键 词：肥厚性心肌病 导管消融术 随访研究 治疗 

分 类 号：R542.2[医药卫生—心血管疾病]