半胱胺对大鼠生长及免疫的影响  

Effect of Cysteamine on Growth and Immuno-function of Rats

作　　者：王恩秀[1] 陈伟华[1] 李燕[1] 韩正康[1] 

机构地区：[1]农业部动物生理生化重点实验室,南京210095

出　　处：《畜牧兽医学报》2002年第6期555-558,共4页ACTA VETERINARIA ET ZOOTECHNICA SINICA

摘　　要：离乳大鼠和 1 60g左右大鼠每周口服半胱胺一次 (1 0 0mg/kgBW) ,结果发现半胱胺能明显促进 1 60g左右大鼠的增重 ,却对离乳大鼠没有明显效果。两组处理均发现大鼠血清生长激素水平显著升高 ,但是后者血清IGF I水平较前者具有更强的升高趋势。结果揭示 ,半胱胺的促生长作用与动物的生长周期密切相关 ,而且这种状况很可能由IGF I水平所决定。半胱胺处理大鼠引发诸多免疫指标的改变 。Weanling and 160 g or so rats were administrated with cysteamine(CS)(100 mg/kg BW)via stomach tube once a week.The results show that CS can not promote the former rats' growth rate while it can apparently promote the later.Although the level of GH both rose in the two groups,the IGF 1 level rose higher in later than the former.It hints that the growth promotion effect of CS is according to the development of animal and IGF 1 may play a key role in this progress.As many indexes of immunofunction have changed after the treatment by CS,we can induce that CS can affect immuno function directly or via the change of some hormones.

关 键 词：半胱胺 大鼠 生长 免疫 

分 类 号：S852.42[农业科学—基础兽医学]