^(99m)Tc-ECD brain SPECT imaging　in patients with acquired　immunodeficiency syndromes  

作　　者：XU Hao, WU Qiu-Lian, LUO Jin-Xiang, CHEN Jian (The First Affiliated Hospital, Medical College of Jinan University, Guangzhou 510630) 

出　　处：《Nuclear Science and Techniques》2002年第2期79-83,共5页核技术（英文）

摘　　要：In order to investigate the changes of regional cerebral blood flow(rCBF) in patients with acquired immunodeficiency syndromes (AIDS), 99mTc-ECDbrain SPECT imaging was performed in 5 patients with AIDS and 16 sex and agematched normal controls, and the rCBF percentages compared to the cerebellum werecalculated using a semi-quantitative processing software. Hypoperfusions in the rightand left frontal, temporal, porietal lobe, basal ganglia and left thalamus were seen in1 patient with dementia. Hypoperfusions in the right and left frontal and temporallobe were seen in 4 asymptomatic patients. The rCBF in the right and left frontal.temporal, porietal lobe, basal ganglia and thalamus, front and pons were decreasedsignificantly in patients with AIDS than those of the control subjects (p ＜0.005). Itis concluded that there exists reduced cortico-subcortical rCBF in AIDS patients.In order to investigate the changes of regional cerebral blood flow (rCBF) in patients with acquired immunodeficiency syndromes (AIDS), 99mTc-ECD brain SPECT imaging was performed in 5 patients with AIDS and 16 sex and age matched normal controls, and the rCBF percentages compared to the cerebellum were calculated using a semi-quantitative processing software. Hypoperfusions in the right and left frontal, temporal, porietal lobe, basal ganglia and left thalamus were seen in 1 patient with dementia. Hypoperfusions in the right and left frontal and temporal lobe were seen in 4 asymptomatic patients. The rCBF in the right and left frontal, temporal, porietal lobe, basal ganglia and thalamus, front and pons were decreased significantly in patients with AIDS than those of the control subjects (p<0.005). It is concluded that there exists reduced cortico-subcortical rCBF in AIDS patients.

关 键 词：头部SPECT造影 ^99MTC-ECD 免疫缺乏综合症 

分 类 号：R817.4[医药卫生—影像医学与核医学]