陕西、青海、新疆三省(区)部分人群庚型肝炎病毒血清学调查  

Seroepidemiologic survey of hepatitis G virus in selected population of Shanxi,Qinghai and Xinjiang Provinces (region) of China

作　　者：曹茂开[1] 刘赴平[1] 姜双应 邵锡如 兰科学[3] 李新兰 张正学[3] 王文 赵文明[1] 黄瑞华[1] 

机构地区：[1]西安交通大学,西安710049 [2]青海省防疫站 [3]解放军第十二医院 [4]乌鲁木齐新疆自治区卫生防疫站 [5]西安中心血站

出　　处：《中华实验和临床病毒学杂志》2002年第4期345-347,共3页Chinese Journal of Experimental and Clinical Virology

基　　金：‘8 63’"中国株HGV GBV C分子生物学研究"西北协作课题

摘　　要：目的　调查陕西、青海、新疆三省 (区 )部分人群庚型肝炎病毒 (HGV GBV)血清学特征。方法　采用ELISA方法 ,共调查三省 (区 ) 14 6 9份血清中GBV IgG抗体。结果　少数民族血清GBV IgG抗体的阳性率 (藏族 4 .11% ,蒙古族 5 .36 % ,维吾尔族 4 .5 5 % ,回族 4 .0 0 % )略高于汉族(1 36 %～ 1 73% ) ,但差异无显著性 (P >0 0 5 ) ;吸毒人群GBV IgG阳性率 (11 30 % ,34 30 1)明显高于正常人群 (2 4 4 % ,18 736 ) ,(P <0 0 1) ;献血员GBV IgG阳性率为 1 0 2 %～ 7 6 8%。结论　三省区民族间GBV IgG抗体阳性差异无显著性 ,血源性传播是其重要途径 ,应加强对献血员及吸毒人员的监管。Objective To observe the serological features of hepatitis G virus (HGV or GBV) in selected population of Shaanxi,Qinghai and Xinjiang Provinces (region).Methods Enzyme linked immunosorbent assay (ELISA) was used to determine IgG antibody against GBV (anti GBV IgG) in serum specimens of 1 469 individuals from the 3 provinces (region).Results The positivity rate of serum GBV IgG antibody in ethnic minorities (4.11% in Tibetan, 5.36% in Mongolian, 4.55% in Uigur, 4.00% in Hui population) was slightly higher than that in Han population (1 36% 1 73%),but the differences were not significant ( P >0.05).The positivity rate of serum GBV IgG antibody in drug abusers (11.30%,34/301) was remarkably higher than that of the normal population (2.44%,18/736) ( P <0.01).The positivity rate of serum GBV IgG antibody in blood donors was 1 02% 7.68%.Conclusion The positivity rates of serum GBV IgG antibody among ethnic groups in the 3 provinces (region) had no significant differences;blood borne transmission seemed to be an important transmission route of GBV,therefore supervision of blood donors and drug abusers should be intensified.

关 键 词：陕西 青海 新疆 庚型肝炎 庚型肝炎病毒 血清学调查 吸毒人群 献血员 

分 类 号：R181.3[医药卫生—流行病学]