硬膜外连续泵注罗哌卡因与芬太尼在分娩镇痛中的应用  

Application of continuous epidural analgesia with ropivacaine and fentanyl during delivery

作　　者：罗晓青[1] 高雪松[1] 彭雪梅[2] 林锦绒[1] 

机构地区：[1]暨南大学医学院第一附属医院妇产科,广东广州510630 [2]暨南大学医学院第一附属医院麻醉科,广东广州510630

出　　处：《第一军医大学学报》2002年第12期1121-1122,共2页Journal of First Military Medical University

摘　　要：目的观察硬膜外连续泵注罗哌卡因与芬太尼用于分娩镇痛的有效性和安全性。方法选择足月、头位、初产产妇98例,产程进展宫口开至3 cm时,行硬膜外腔穿刺置管,用0.2%罗哌卡因+2 μg/ml芬太尼的混合液给药,首次剂量5 ml,之后用微量镇痛泵持续硬膜外腔给药,至宫口开全停药。对照组98例未行分娩镇痛。结果行分娩镇痛组产妇用药后疼痛明显减轻(P<0.001),产程中活跃期明显缩短(P<0.05),对母胎无明显影响。结论硬膜外连续泵注罗哌卡因与芬太尼用于分娩镇痛效果好,实施简便,有助产程进展。s: Objective To evaluate the safety and efficiency of ropivacaine and fentanyl for continuous epidural analgesia during delivery. Methods Altogether 98 full-term primigravidas with vertex presentation were selected for this study. Epidural catheter was placed during delivery with the cervical dilation of 3 cm, and the mixture of 0.2% ropivacaine and 2 μg/ml fentanyl at the initial dose of 5 ml was given for continuous epidural analgesia. Drug infusion was discontinued when the second stage of delivery started. Another 98 primigravidas of similar conditions without analgesia served as the control group. Results Analgesic group showed obvious pain-relieving effect (P<0.001) during the delivery, in which the active phase was significantly shortened (P<0.05). No obvious adverse effect arose in the mother and fetuses from the administration of analgesia. Conclusion Continuous epidural analgesia by pumping ropivacaine and fentanyl is effective and convenient for pain relief during delivery, and can be beneficial to the smooth progress of delivery.

关 键 词：镇痛 硬膜外注射 微量泵 罗哌卡因 芬太尼 剂量 无痛分娩 

分 类 号：R614[医药卫生—麻醉学]