乌蔹莓挥发油成分及其抗病毒活性  

Constituents and Anti-virus Activity of Essential Oil from Cayratia japonca

作　　者：罗莉 廖时萱[2] 梁华清[2] 朱洪平[2] 朱可[3] 貌盼勇[4] 杨慧武[4] 白雁平[4] 李泉根 

机构地区：[1]解放军空军上海第一医院,200031 [2]第二军医大学药学院植物化学教研室,200433 [3]解放军401医院,青岛266071 [4]解放军302医院,北京100039

出　　处：《第二军医大学学报》1992年第2期169-173,共5页Academic Journal of Second Military Medical University

摘　　要：用GC/MC/DC法分离乌蔹莓挥发油得到85个峰,经解析鉴定出30个成分;乌蔹莓挥发油对小鼠感染流感病毒A_3型和细胞感染单纯疱疹病毒Ⅰ型均具有明显抗病毒活性,特别是对单纯疱疹病毒Ⅰ型在细胞中复制的抑制作用可与无环乌苷媲美。Essential oil of Cayratia japonica was separated into 85 peaks by means of GC/MS/DS and 30 peaks of them were identified. The oil showed pronounced antiviral activities against influenza virus A, in vivo and herpes simplex virus 1 (HSV-1) in vitro. The inhibitory effect of the oil on replication of HSV-1 in Hela cells was comparable to that of acyclovir (ACV).

关 键 词：乌敛莓 挥发油 抗病毒剂 小鼠 

分 类 号：R282.710.5[医药卫生—中药学]