声学密度定量技术评价风湿性二尖瓣病变的程度-与X线和病理检查对比分析  

Quantitative Evaluation of the Degree of the Rheumatic Mitral Valve Lesions Using Acoustic Densitometry

作　　者：马春燕[1] 任卫东[1] 杨军[1] 唐力[1] 陈昕[1] 傅志民[2] 

机构地区：[1]中国医科大学第一临床学院心功能科,沈阳市110001 [2]中国医科大学第一临床学院病理科,沈阳市110001

出　　处：《中国超声医学杂志》2002年第12期916-918,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 :探讨声学密度定量 (AD)技术评价风湿性二尖瓣病变程度的临床应用价值。方法 :应用 AD技术检测 39例欲行机械二尖瓣置换术的风心病患者和 4 0例正常对照者二尖瓣 (MV)的标化背向散射积分 (IBS% )参数 ,并对术中切除的 MV标本进行 X线检查 ,将其分为纤维化组和钙化组。对纤维化组 MV进行病理检查。结果 :钙化组 MV IBS%参数值最大 ,其次为纤维化组 ,并且不同纤维化程度二尖瓣之间的 IBS%值差异显著 (P<0 .0 5～ P<0 .0 0 1) ;最大的 IBS% >75 %诊断 MV钙化的灵敏度和特异度分别为 90 .4 8%和 94 .4 4 %。结论 :AD技术可以定量评价风湿性二尖瓣病变的程度 ,为风心病的临床治疗提供客观的依据。Objective:To discuss the clinical significance of quantitative assessment of the degree of rheumatic mitral valve(MV)lesions using acoustic densitometry(AD).Methods:Thirty nine patients with rheumatic MV lesions scheduled to undergo mitral replacement and 40 control subjects were examined with AD.The integrated backscatter(IBS)parameters(mean and maximal percent IBS)were measured.The 39 excised MV were evaluated radiographically and pathologically.Results:The values of mean and maximal percent IBS in patients with rheumatic MV lesions were larger than in those in controls( P <0 05～ P <0 001),and there were significant differences among the differnet fibrotic stages of MV in patients with fibrotic MV.The maximal percent IBS more than 75% predicted valve of calcification with a sensitivity of 90 48% and specificity of 94 44% respectively.Conclusions:AD can quantitatively evaluate the degree of MV fibrosis and assess calcification.

关 键 词：声学密度定量技术 风湿性二尖瓣病变 病理 对比分析 超声心动图 X线诊断 

分 类 号：R541.2[医药卫生—心血管疾病]