寄生虫病细胞工程学免疫防治研究  

Research on Prevention and Treatment of Parasitoses by Immunity of Cytological Engineering Technique

作　　者：张中庸[1] 李靓如[1] 张京 曾宪芳[1] 易新元[1] 言敢威[1] 曾庆仁[1] 马春艳 吴莲英 章洁[1] 

机构地区：[1]中南大学湘雅医学院血吸虫病研究室,湖南长沙410078 [2]天津市实验动物研究所,天津300381

出　　处：《天津农学院学报》2002年第4期1-4,共4页Journal of Tianjin Agricultural University

基　　金：国家 九五"两项重大科技攻关项目(96-005-02-02-06;96-005-02-05);国家自然科学基金项目"血吸虫细胞培养与建系研究"(30170840);农业部重大疾病防治基金项目"血吸虫病防治方法与方案研究"(200114704)

摘　　要：寄生虫病细胞工程学免疫防治研究,经历了20余a,首先在中国获得成功。在国家 九五"两项重大科技攻关项目支持下,建立了猪囊尾蚴CC-97细胞系,研制成功了猪囊尾蚴细胞疫苗;2000年以来,在国家自然科学基金等基金支持下,日本血吸虫幼虫———毛蚴、尾蚴和成虫细胞体外培养相继获得成功,开创了血吸虫病细胞工程学免疫防治的新局面。After more than twenty years' study, researches on prevention and treatment of parasitoses by immunity of cytological engineering technique first succeeded in China. Under the supports of two item Grants(No. 96005020206;No.960050205)from the Key Science and Technique Project in National '9·5' of China, a CC97 immune cell line of Cysticercus cellulosae and its cell vaccine were established.Since 2000,under the supports of Fund of National Natural Science of China (No.30170840), and Fund of Prevention and Treatment of Major Disease of Agricultural Ministry (No.200114704), the Schistosoma japonicum cells were successful in in vitro cultivations,which derived from miracidia, cercariae and adult of Schistosoma japonicum. Thus,a new prospect in prevention and treatment of Schistosomaisis has been opened up by immunity of cytological engineering technique.

关 键 词：免疫防治 寄生虫病 细胞工程学 猪囊尾蚴细胞系 细胞疫苗 日本血吸虫 

分 类 号：S855.9[农业科学—临床兽医学] S852.[农业科学—兽医学]