肾炎灵颗粒剂对慢性原发性肾小球疾病氧自由基代谢的影响  

Effects of Shen Yanlin Granulae on Oxide Free Radical Reaction of CGN

作　　者：孙伟[1] 曾安平[1] 王钢[1] 邹燕勤[1] 邵家德[1] 

机构地区：[1]江苏省中医院全国中医肾病医疗中心,江苏南京210029

出　　处：《中国中医基础医学杂志》2002年第11期28-29,42,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：江苏省科委课题

摘　　要：目的 :探讨肾炎灵颗粒剂治疗慢性肾炎、难治性肾病综合征的作用机理。方法 :以肾炎灵颗粒剂治疗慢性肾炎和难治性肾病综合征 ,检测治疗前后患者的过氧化脂质 (LPO)、血浆和红细胞的超氧阴离子和SOD活性。结果 :肾炎灵颗粒剂能明显降低患者的过氧化脂质 (LPO)、血浆和红细胞的超氧阴离子 ,提高SOD活性。结论 :肾炎灵颗粒剂调整慢性肾炎、难治性肾病综合征患者的氧自由基代谢 ,可能是其临床疗效作用机理的一个组成部分。The effects and therapeutic mechanism of Shen YanLin granulae on CGN,RNS were studied further.Methods:The patients with CGN,RNS were treated by Shen YanLin granulae.The serum LPO,serum and erythrocyte O -· 2 and serum SOD activity of the patients were examined in treatment beginning and end.Results:It was found that the precription could reduce the serum LPO,serum and erythrocyte O -· 2 ,increase the serum SOD activity of the patients.Couclusion:The adjusting oxide free radical reaction may be the one of the effects and therapeutic mechanism of Shen YanLin granulae on CGN,RNS.

关 键 词：肾小球疾病 肾炎灵颗粒剂 氧自由基代谢 作用机理 中医药疗法 

分 类 号：R277.526[医药卫生—中医学]