Interaction between Bifunctional Dioxo Macrocyclic Polyamine Co(II) Complex and DNA in Metallomicellar System  

作　　者：QingXiangXIANG HongZHOU 等 

机构地区：[1]DepartmentofChemistry,SichuanUniversity,Chengdu610064 [2]CollegeofLifeScience,SichuanUniversity,Chengdu610064

出　　处：《Chinese Chemical Letters》2002年第3期223-226,共4页中国化学快报（英文版）

基　　金：We are thankful to the National Natural Science Foundation of China for financial support; (No. 29872027).

摘　　要：The cleavage of DNA (pUC18) by lipophilic macrocyclic polyamine Co(II) complex was investigated in metallomicellar system. The results showed that the conversion of plasmid DNA (pUC18) increases with the increase of the concentration of complex under physiological conditions.The cleavage of DNA (pUC18) by lipophilic macrocyclic polyamine Co(II) complex was investigated in metallomicellar system. The results showed that the conversion of plasmid DNA (pUC18) increases with the increase of the concentration of complex under physiological conditions.

关 键 词：Bifunctional dioxo macrocyclic polyamine COMPLEX micellar system cleavage of DNA. 

分 类 号：O641.4[理学—物理化学] O614.[理学—化学]