Synthesis of Cholest-5-en-24-oxo-3b, 19-Diacetate  

作　　者：Wei Gang LU Ming Yan WANG Jing Yu SU Long Mei ZENG 

机构地区：[1]School of Chemistry and Chemical Engineering,Zhongshan University,Guangzhou 510275

出　　处：《Chinese Chemical Letters》2002年第2期119-120,共2页中国化学快报(英文版)

基　　金：We are grateful to the National Natural Science Foundation of China (No. 29932030) and Natural Science Foundation (No. 970154) of Guangdong Province for financial support for this work.

摘　　要：Cholest-5-en-24-oxo-3, 19-diacetate was synthesized starting from stigmasterol 3 via seven step reactions in 21.0% overall yield. It can be served as a key intermediate for the synthesis of many biologically active 19-hydroxylated sterols.Cholest-5-en-24-oxo-3, 19-diacetate was synthesized starting from stigmasterol 3 via seven step reactions in 21.0% overall yield. It can be served as a key intermediate for the synthesis of many biologically active 19-hydroxylated sterols.

关 键 词：Hydroxylated sterol SYNTHESIS IRRADIATION ozonolization. 

分 类 号：O623.624[理学—有机化学]