1,3-Dipolar Cycloaddition of Substituted Benzonitrile Oxide to 5-(R)-(l-Menthyloxy)-2(5H)-furanone  

作　　者：HaiHongHUANG QingHuaCHEN 等 

机构地区：[1]InstituteofMateriaMedica,ChineseAcademyofMedicalSciences＆PekingUnionMedicalCollege,Beijing100050 [2]DepartmentofChemistry,BeijingNormalUniversity,Beijing100875

出　　处：《Chinese Chemical Letters》2002年第7期593-596,共4页中国化学快报（英文版）

摘　　要：Several isoxazoline compounds were obtained by the 1,3-dipolar cycloaddition of benzonitrile oxide to 5-(R)-(l-menthyloxy)-2(5H)-furanone. The reaction condition was investigated preliminarily, the structures of these compounds have been established via the analysis of NMR data(involved NOEID or HMBC) and the reaction seems occurred regioselectively.Several isoxazoline compounds were obtained by the 1,3-dipolar cycloaddition of benzonitrile oxide to 5-(R)-(l-menthyloxy)-2(5H)-furanone. The reaction condition was investigated preliminarily, the structures of these compounds have been established via the analysis of NMR data(involved NOEID or HMBC) and the reaction seems occurred regioselectively.

关 键 词：Dipolar cycloaddition benzonitrile oxide CONFIGURATION 1H-NMR NOE. 

分 类 号：O626.11[理学—有机化学] O625[理学—化学]