4,5-咪唑双酰腙的合成与表征  

Synthesis and Characterization of Imidazazole-4,5-diacylhydrazones

作　　者：覃江克[1] 苏桂发[1] 倪青玲[1] 牟红涛[1] 谢建武[1] 黄世稳[1] 

机构地区：[1]广西师范大学化学化工系,广西桂林541004

出　　处：《合成化学》2002年第5期464-467,共4页Chinese Journal of Synthetic Chemistry

基　　金：广西师范大学青年科学基金资助课题

摘　　要：以酒石酸为原料 ,经成环制酸、酯化、肼解、与芳香醛缩合 ,制备了 7个 4 ,5 -咪唑双酰腙 ,并用元素分析 ,IR,1H NMR,13 C NMR对它们的结构进行了表征。实验结果表明 ,酰肼与芳香醛在冰醋酸中进行缩合酰腙化一步 ,具有反应快速、产率高、条件温和。Imidazole-4,5-dicarboxylic acid, which was got from tartaric acid by cyclization, was esterified, hydrazinnolized and then condensated with aroyladehydes in glacial acetic acid to synthesize seven new imidazole-4,5-diacylhydrazones in mild condition with high yield, especially the condensation reaction was finished very quickly(from several seconds to several minutes) and the work-up was simple too. These new compounds were characterized by elementary analysis, IR, 1H NMR and 13C NMR.

关 键 词：4 5-咪唑双酰腙 合成 表征 缩合 酒石酸 酰肼 芳香醛 

分 类 号：O626.23[理学—有机化学]