常压氧与高压氧联合治疗重型颅脑损伤  

EFFECT OF COMBINATION OF NORMOBARIC AND HYPERBARIC OXYGEN THERAPY IN 87 CASES OF SEVERE CRANIOCEREBRAL INJURY

作　　者：卢晓欣[1] 汤永建[1] 何苏育[1] 

机构地区：[1]福州总医院高压氧科

出　　处：《福州总医院学报》2002年第3期146-147,共2页Journal of Fuzhou General Hospital

摘　　要：目的:探讨有合并症的重型颅脑损伤病人的合理氧疗方案,以提高治愈率和有效率。方法:87例有高压氧治疗禁忌症的重型颅脑损伤病人分为2组,分别采用早期常压下面罩或呼吸活瓣吸纯氧(常压氧疗法)+高压氧的联合疗法和高压氧疗法两种方案治疗,比较其有效率和治愈率。结果:常压氧+高压氧治疗组有效率、治愈率均高于高压氧组,其中治愈率差别具有显著意义(P<0.05);常压氧+高压氧组开始治疗的时间明显早于高压氧组,治疗开始的早晚与疗效直接相关,越早治疗治愈率越高。结论:尽早合理应用常压氧+高压氧联合疗法,不失为促进伤后脑组织功能恢复、降低残死率和提高生存质量的有力措施之一。Objective: To explore the oxygen therapy regime in severe craniocerebral injury patients so as to raise the healing rate and efficacy rate. Methods: Eighty-seven sessions of craniocerebral injury patients with various abstinences for hyperbaric oxygen therapy were divided into two groups. One of the group (57 sessions, group A) was treated with an early normobaric pure oxygen inhilation with face mask (normobaric oxygen therapy) followed by a hyperbaric oxygen therapy after the abstinences vanished and the other group (30 sessions, group B) with merely a hyperbaric oxygen therapy. Efficacy rates as well as healing rates were compared between the two groups. Results: Both efficacy rate and healing rate were higher in group A when compared to group B with the healing rate significant difference (P< 0.05). Beginning of the treatment in group A was much earlier than in group B and the earlier the oxygen therapy began, the higher the healing rate. Conclusion : A resonable application of normobaric and hyperbaric oxygen therapies as early as possible was an effective measurement for accelerating the recovery of brain function, lowering the disablement rate and mortality rate and raise the survival quality in servere craniocerebra injuries.

关 键 词：常压氧 高压氧 联合治疗 重型颅脑损伤 

分 类 号：R651.15[医药卫生—外科学] R459[医药卫生—临床医学]