小剂量rt-PA结合追加静脉滴入治疗难溶性老年急性心肌梗死研究  

Low-dose rt-PA and combine with the second continuous intravenous dose for treatment of the senile patients with acute myocardial infarction

作　　者：宋远民[1] 郑瑾[1] 吕泉江 周乃胜[1] 李兵[1] 

机构地区：[1]青岛市海军401医院干一科,266071

出　　处：《实用心脑肺血管病杂志》2002年第6期326-327,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的　探讨rt PA静脉溶栓治疗急性心肌梗死新方法 ,提高溶栓成功率 ,降低药物费用。　方法　对2 2例急性Q波心肌梗死 ,给予静脉小剂量rt PA 5 0mg ,给药 90分钟未溶栓成功患者 ,立即追加静脉滴入rt PA 5 0mg ,每分钟 0 5mg～ 1 0mg ,溶栓成功停止静滴 ,或直到 5 0mg静脉滴完为止。　结果　 2 2例患者初溶 17例成功 ,其余 5例不成功者通过追加静脉滴入全部溶栓成功。　结论　小剂量rt PA结合追加静脉滴入溶栓治疗急性心肌梗死 ,可提高溶栓成功率 ,减少整体溶栓药物剂量 ,降低费用 ,值得进一步研究。Objective To study the new method of intravenous thrombolysis treatment with rt PA for acute myocardial infarctions(AMI),increase successful rate of thrombolysis and reduce drug costs Methods Low dose rt PA(50mg) was given intravenously in 22 patients with acute myocardial infarctions As the patients having been not succeeded for thrombolysis by 90 minutes after the first dose,they were immediately given the second dose of rt PA 50 mg by continuous intravenous route,0 5mg/min～1 0mg/min,until succeseful or completing the dose Results 17 patients were successfully thrombolized by the first dose,other 5 patients were finally succeeded by using the second dose Conclusion Low dose rt PA and combine with the second continuous intravenous dose for treatment of acute myocardial infarction could increase successful rate of thrombolysis,which did not only reduced the dose,of rt PA,but also decresed the drug costs

关 键 词：治疗 急性心肌梗死 静脉溶栓 RT-PA 追加静滴 老年人 AMI 

分 类 号：R542.22[医药卫生—心血管疾病]