黄芪建中汤联合督脉灸治疗消化性溃疡临床研究  

Clinical Research on the Treatment of Peptic Ulcer by Huangqi Jianzhong Decoction Combined with Governor Meridian Moxibustion

作　　者：魏晏[1] 魏明[2] 

机构地区：[1]河南中医学院第三附属医院,河南郑州450008 [2]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2015年第6期874-877,共4页Acta Chinese Medicine

基　　金：国家科技部十一五科技支撑计划(2007BAI20B094);河南省科技厅科技攻关项目(112102310112)

摘　　要：目的:探讨黄芪建中汤加减联合督脉灸治疗脾胃虚寒型消化性溃疡患者的临床疗效及其对患者生活质量的影响。方法:将符合脾胃虚寒型消化性溃疡诊断标准的80例患者按随机数字表法(1∶1)分为两组。治疗组40例,采用黄芪建中汤加减联合督脉灸方法治疗;对照组40例,给予口服奥美拉唑肠溶胶囊和阿莫西林克拉维酸钾。两组1疗程均为6周。治疗前后观察中医证候评分、焦虑自评量表(self-rating anxiety scale,SAS)及抑郁自评量表(self-rating depression scale,SDS)评分及SF-36健康调查量表中的患者躯体功能、躯体疼痛、躯体职能、情感职能、总体健康、生命活力、社交功能和心理健康8个维度进行评价等指标的变化,随访观察0.5~1.0 a并统计其复发率。结果:1两组有效率分别为对照组为82.50%,治疗组为95.00%,两组总体疗效比较,治疗组优于对照组Z=-4.116,P=0.000。2两组患者治疗后的SF-36健康调查量显示:治疗组躯体疼痛、躯体职能、总体健康、生命活力和心理健康评分较治疗前均明显降低(P<0.05),对照组躯体疼痛、生命活力和心理健康评分较治疗前均明显降低(P<0.05),且治疗组优于对照组(P<0.05)。3两组患者治疗后SDS、SAS评分较治疗前均明显降低(P<0.05),且治疗组优于对照组(P<0.05)。4两组患者治疗后的中医证候评分较治疗前明显降低(P<0.05),且治疗组明显优于对照组(P<0.05)。5两组治疗后生活质量积分较治疗前明显降低(P<0.05),且治疗组明显优于对照组(P<0.05)。6对照组4例患者出现口干、口渴、头隐疼不适,治疗组有1例出现大便稀,1例恶心不适,1例口干、口渴等。结论:黄芪建中汤加减联合督脉灸治疗脾胃虚寒型消化性溃疡疗效显著,能够明显改善患者的生活质量及焦虑抑郁状态,且不良反应较少。Objective:To explore the clinical research and influence of patients on the treatment of peptic ulcer by Huangqi Jianzhong Decoction combined with du-meridian moxibustion. Methods:80 cases with syndrome of deficiency-cold in spleen and stomach were randomly divided into two groups. The treatment group(40 cases) was given Huangqi Jianzhong Decoction combined with du-meridian moxibustion. The control group was take orally OME enteric capsule and potassium amoxicillin clavulanate. One course is 6 weeks. Observed the syndrome of Chinese medicine grade,self-rating anxiety scale and self-rating depression scale grade. Patients in the SF-36 health survey scale body function,body pain,physical function,emotional function,general health,vitality,social function and mental health evaluation indicators such as changes of eight dimensions were followed for 0. 5- 1. 0 year and its recurrence rate statistics. Results:1two groups of efficient control group respectively was 82. 50%,the treatment group was 95. 00%,two groups of overall curative effectcomparison,the treatment group is better than that of control group Z = 4. 116,P = 0. 000). 2Two groups of patients after treatment of SF-36 health survey showed that the treatment group the body pain,body function and overall health,vitality and mental health scores were significantly lower( P < 0. 05) and control group in the body pain,life and mental health scores were significantly lower( P <0. 05),and the treatment group is better than that of control group( P < 0. 05). 3 Two groups after treatment in patients with SDS and SAS scores were significantly lower( P < 0. 05),and the treatment group is better than that of control group( P < 0. 05). 4Two groups of patients after treatment of TCM symptom score were significantly decreased( P < 0. 05),earlier and the treatment group was better than control group( P < 0. 05). 5In the two groups after treatment significantly lower life quality points from the previous( P < 0. 05),and the treatment group was better than control group( P < 0

关 键 词：消化性溃疡 脾胃虚寒证 黄芪建中汤 督脉灸 生活质量 

分 类 号：R259[医药卫生—中西医结合]