对胎儿胃粘膜嗜铬粒A和胃泌素细胞的观察  

Survey on the fetus gastro-mucous membrane CGA and G cells

作　　者：张辉[1] 齐效勇[1] 赵铁军[1] 范蓝欧[2] 马春梅[2] 张世棋[2] 

机构地区：[1]张家口医学院解剖学教研室,075029 [2]张家口医学院大学生科协,075029

出　　处：《中国优生与遗传杂志》2002年第6期66-66,68,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的　探讨不同胎龄胃粘膜内CGA和G细胞的形态和数量。方法　收集不同胎龄的胃窦粘膜标本 39例 ,SP免疫组织化学方法 ,显示CGA和G免疫阳性细胞 ,以图像分析仪测定不同胎龄的CGA和G细胞数密度和面密度。结果　 2 1～ 2 4wCGA数密度和面密度分别为 0 0 4 1± 0 0 2 0 ,1 52 1± 0 60 1。G细胞分别为 0 0 2 6± 0 0 1 4 ,0 893± 0 2 0 5 ;38～ 41w时CGA为 0 1 0 4± 0 0 4 9,3 0 1 8± 0 935。G为 0 0 36± 0 0 1 8,1 394± 0 582。 38～ 41w组数密度和面密度明显高于 2 1～ 2 6w。 32～ 36w组与 2 1～ 2 4w无明显差异 (P >0 0 5)。结论　CGA和G细胞随胎龄而增高 ,而 36w以后增长速度加快。Objective: To investigate quantitatively the numerical and aual density of CGA and G positive cells in the gastro-mucous membrane in different fetus ages. Methods:39 cases of the stomach sinus membrane samples in the different fetus ages were collected and the SP immuno-chemical method was used to detect the CGA and G immuno-positive cells. Results:CGA number and surface density was 0 041±0 020,1 521±0 601,respectively from 21～24weeks;G cells were 0 026±0 014,0 893±0 205 respectively.From 38～41weeks,CGA 0 104±0 049,3 018±0 935;G cells were 0 036±0 018,1 394±0 582.The number and surface density in 38～41 week group was significantly in cuared than that in 21～26 week group.Between 32～36 and 21～24 week group it was no obvious difference(P>0 05).The article described and analysed the form and meaning of the secretory cells in the gastro-mucous membrane.Conclusion:CGA and G cells were increased with the fetus ages and grow rapidly after 36 weeks.The differentiation of endocrine cells was earlier than that of the gastric exocrine gland cells.

关 键 词：胎儿 嗜铬粒A细胞 胃泌素细胞 免疫组织化学 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]