血液灌流清除人体内毒鼠强的研究  

Study on the effect using hemoperfusion to treat tetramine poisoned patients

作　　者：葛晓伟[1] 李晓华[1] 关蕾[1] 马沛滨[2] 王海石[3] 

机构地区：[1]中国疾病预防控制中心职业卫生与中毒控制所中毒控制中心,北京100050 [2]徐州市第三人民医院中毒科 [3]山东省立医院中毒与职业病科

出　　处：《中华劳动卫生职业病杂志》2002年第6期403-404,共2页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：目的　评价血液灌流清除人体内毒鼠强的效果。方法　用气相色谱法监测 3例毒鼠强中毒患者在血液灌流过程中灌流器进口和出口、血液灌流后 72h内患者血中毒鼠强浓度变化以及灌流器中毒鼠强的吸附量。结果　血液灌流器进口处患者血液中毒鼠强浓度在灌流过程中基本保持不变 ;血液灌流后 72h内患者体内毒鼠强浓度变化不大 ;血液灌流器吸附毒鼠强 1 .0 3～ 1 .55mg。结论　血液灌流虽然不能够有效降低患者血液中毒鼠强浓度 ,但一次灌流能清除Objective To evaluate the effect of hemoperfusion on tetramine poisoned patients. Methods Three tretramine poisoned cases treated with hemoperfusion were selected.The samples during and after hemoperfusion were collected and analyzed by gas chromatography. Results Tetramine concentration at the inlet of the artificial kidney kept the same level during hemoperfusion.After hemoperfusion,the tetramine concentration in patient plasma changed little in 72 hours.1.03～1.55 mg of tetramine was adsorbed by the instrument of hemoperfusion after two hours' hemoperfusion. Conclusion Although hemoperfusion was not so effective to reduce blood tetramine concentration in patients,it could clear about 1 mg tetramine for one time.

关 键 词：血液灌流 毒鼠强 中毒 气相色谱法 

分 类 号：R595.4[医药卫生—内科学]