胃起搏对术后胃动力影响的实验研究  

The Experimental Study of the Influence of Applying Gastric Pacing to Postsurgical Gastric Dynamic

作　　者：李富宇[1] 何生[1] 于运海 毛辉[1] 

机构地区：[1]四川大学华西医院普外科,成都610041 [2]黑龙江省讷河市第一人民医院,讷河161300

出　　处：《中国普外基础与临床杂志》2003年第1期33-35,共3页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的　探讨胃起搏在术后胃轻瘫治疗中的可行性及疗效。方法　在术后急性胃轻瘫动物模型的基础上分别应用胃起搏和静脉注射红霉素 (1mg/kg) ,观察胃动力学指标的改变。 结果　胃起搏组和红霉素组胃窦压及胃窦 十二指肠压力差均显著高于对照组基础压 (P<0 .0 1 ) ;胃起搏组胃窦压及胃窦 十二指肠压力差又高于红霉素组 (P<0 .0 5) ,但两组十二指肠内压差异无显著性意义 (P>0 .0 5)。胃起搏 2h的胃排空率为 (66 .37± 7.2 1 ) % ,高于静脉注射红霉素 2h的胃排空率〔(49.92± 9.2 7) % ,P<0 .0 1〕。结论　高频胃起搏能明显改善胃动力学指标 ,可用于术后胃轻瘫的治疗 。Objective To explore the feasibility and curative effect of gastric pacing on postsurgical gastroparesis. Methods The indexes of gastric dynamic of applying gastric pacing to the experimental animal model of acute postsurgical gastroparesis was compared with that of injecting erythromycin (1 mg/kg).Results The pressure of gastric antrum and the pressure gradient between gastric antrum and duodenum were respectively higher than basic pressure in the two experimental groups ( P <0.01); Except duodenal pressure, the indexs of gastric dynamic of pacing group were higher than that of erythromycin group ( P <0.05). The gastric emptying rate of pacing group 〔(66.37±7.21)%〕 was higher than erythromycin group 〔(49.92±9.27)%, ( P <0.01)〕. Conclusion Higher frequency gastric pacing can improve the indexes of gastric dynamic and be applied to treat postsurgical gastroparesis, its effect may be better than erythromycin.

关 键 词：胃起搏 胃动力学 术后胃轻瘫 红霉素 

分 类 号：R656.61[医药卫生—外科学]