急性胆管炎病人血清α-谷胱甘肽-S-转移酶的检测及意义  

Detecting and its significance of serum α-glutathione-S-transferase in patients of acute cholangitis

作　　者：戴东[1] 曾宪成[1] 李国光[1] 杜松涛[1] 李浩[2] 李哲浩[2] 汪树根[3] 

机构地区：[1]广东医学院附属医院外科,广东湛江524001 [2]延边大学医学院附属医院普通外科,吉林延吉133000 [3]中山大学附属医院器官移植科,广东广州510080

出　　处：《延边大学医学学报》2002年第3期184-186,共3页Journal of Medical Science Yanbian University

摘　　要：[目的 ]探讨血清α 谷胱甘肽 S 转移酶 (α GST)在急性胆管炎病人肝功能异常检测中的临床应用价值 .[方法 ]实验组为 32例急性胆管炎病人 ,对照组为 2 0例健康志愿者 .α GST检测采用酶联免疫法 ,谷丙转氨酶、谷草转氨酶检测采用常规生物化学方法 .[结果 ]急性胆管炎病人血清α GST升高 ,发病早期α GST升高快于谷丙转氨酶、谷草转氨酶 ,经治疗后α GST下降快于谷丙转氨酶、谷草转氨酶 .[结论 ]αOBJECTIVETo study the value of clinic application of detecting the serum α-glutathione-S-transferase (α-GST) as a marker of liver function in patients of acute cholangitis.METHODSThe experimental group includes 32 patients of acute cholangitis and control group includes 20 healthy volunteers. α-GST was detected by enzyme immunoassay(EIA) and ALT and AST by routine biochemistry methods.RESULTSThe α-GST was increased in patients of acute cholangitis, the increase of α-GST was faster than ATL and AST in early stage and drops faster than ALT and AST after treatment.CONCLUSIONα-GST is a more sensitive marker of liver function.

关 键 词：急性胆管炎 谷胱甘肽转移酶类 血清诊断 肝功能 

分 类 号：R657.41[医药卫生—外科学]