支气管肺泡灌洗治疗支气管扩张合并感染的疗效分析  

ANALYSIS OF THERAPEUTIC EFFECT THROUGH BRONCHOALVEOLAR LAVAGE ON BRONCHIECTASIS WITH INFECTION

作　　者：江兴堂[1] 江毅芳[1] 苏静苇[1] 

机构地区：[1]厦门大学医学院第一临床学院厦门中山医院呼吸内科,361004

出　　处：《中国内镜杂志》2002年第12期24-25,共2页China Journal of Endoscopy

摘　　要：目的 :探讨支气管肺泡灌洗 (BAL)治疗支气管扩张合并感染的疗效及其安全性。方法 :将 91例支气管扩张合并感染的病人随机分为 4组 :门诊治疗组 (A组 ) 2 6例 ,门诊对照组 (B组 ) 2 3例 ,住院治疗组 (C组 ) 2 2例和住院对照组 (D组 ) 2 0例。对照组采用常规治疗 ,治疗组在常规治疗的基础上 ,加用BAL治疗。观察 4组患者的疗效。结果 :A组疗效明显优于B组 (P <0 .0 1) ,C组疗效也明显高于D组 (P <0 .0 1) ,而A组与C组的疗效比较 ,差异无显著性 (P >0 .0 5 )。治疗过程中 ,有时出现短暂的动脉血氧饱和度下降和心率增快。大部分病例经 1～ 2次BAL治疗后 ,症状消失。结论 :BAL治疗支气管扩张感染 ,具有提高疗效 ,缩短疗程 ,安全和可靠的优点 ,值得在门诊病人中推广。Objective: To study the effect and safety through bronchoalveolar lavage (BAL) on bronchiectasis with infection. Methods: Ninty-one patients with bronchiectasis of infection were randomly divided into 4 groups. Twenty-six subjects in the outpatient curative group(A group), twenty-three subjects in the outpatient control group(B group),twenty-two subjects in the inpatient curative group(C group), twenty subjects in the inpatient control group ( D group). The control group received the old routine.The treatment group were treated with old routine plus BAL. The outcomes of 4 groups were analysed. Results: The effect of A group were far better than the B group ( P <0.01), and C group were much better than the D group ( P <0.01). A group as effect as C group ( P >0.05). The SaO 2 dropped and quicken heart rate of short duration happened sometimes in the course of the treatment. Through one or two times BAL, the symptoms subsided in the great majority of the cases. Conclusions: BAL has therapeutic effect in patients with bronchiectasis with infection, including raise the effect, shorten the course of treatment, safe and reliable. It worth to spread in the outpatients.

关 键 词：疗效 支气管肺泡灌洗 支气管扩张 支气管感染 安全性 血氧饱和度 

分 类 号：R562.2[医药卫生—呼吸系统]