松质骨孔隙率的二维光电检测  

Two-dimension Opto-electronic Test Method to Determine the Cancellous Bone Porosity

作　　者：陈海斌[1] 李德源[2] 廖海洋[3] 刘京诚[3] 肖凯[1] 刘大维[1] 

机构地区：[1]第三军医大学附属大坪医院野战外科研究所,重庆400042 [2]重庆大学工程力学系,重庆400044 [3]重庆大学光电技术及系统教育部重点实验室,重庆400044

出　　处：《重庆大学学报（自然科学版）》2003年第1期58-61,共4页Journal of Chongqing University

基　　金：教育部重点实验室访问学者基金 (教技司 (2 0 0 0 ) 12 3号 ) ;重庆市科委院士基金项目 (渝科委 1998-93 )

摘　　要：采用二维光电检测方法研究松质骨孔隙率沿不同方向的分布规律。新鲜猪胫骨后肢松质骨制备成 36张切片并均分成两组 :一组为沿胫骨轴向的横切切片 ,另一组为垂直于胫骨轴向的纵切切片。经光镜观察和图像分析 ,计算出每张松质骨切片表面的总面积、骨基质的面积、孔隙的面积及该松质骨切片的孔隙率。测试结果表明 :松质骨孔隙率在胫骨轴向沿靠近密质骨的方向逐渐减小 ,在垂直于胫骨轴向方向基本不变 ;松质骨可看作是横观各向同性材料 ;如果切片数足够多 ,采用二维光电检测方法 。A two dimension opto electronic test method has been developed to determine the distribution characteristics of cancellous bone porosity. The fresh pig tibiae concellous bone in behind leg was sectioned. A total of 36 cancellous bone sections were divided two groups. The first group consisted of 18 transversal sections along the axial direction, and the second group consisted of 18 axial sections along the transversal direction of the tibiae. Their images were examined microscopically and processed quantitatively. The total area, solid matrix area and pore area of each specimen and its porosity were determined, too. The cancellous bone porosity is gradually decreased along the axial direction of tibiae and approaching to the compact bone, but almost constant along the transversal direction. Cancellous bone is modeled as a transversely isotropic, liquid saturated porous solid. The two dimension opto electronic test method can be used to relatively accurately determine the distribution characteristics of the cancellous bone porosity from different directions if the cancellous bone sections are enough.

关 键 词：二维光电检测 松质骨 孔隙率 多孔介质 骨移植 微结构 

分 类 号：R318.01[医药卫生—生物医学工程] R68[医药卫生—基础医学]