复方三七口服液对小鼠免疫功能和抗氧化功能的影响  

EXPERIMENTAL STUDY OF THE EFFECTS OF COMPOUND SANQI ORAL LIQOUR ON IMMUNE AND ANTI-OXIDATION FUNCTION IN AGING MICE

作　　者：孙云[1] 邓阳梅[1] 蔡元培 程翔 龚跃新 

机构地区：[1]扬州大学医药研究所,江苏扬州225001 [2]扬州大学 [3]江苏省南京市先声药业股份有限公司,江苏南京210000

出　　处：《江苏临床医学杂志》2002年第6期518-519,共2页Journal of Jiangsu Clinical Medicine

摘　　要：目的 :观察复方三七口服液对衰老小鼠的免疫功能和抗氧化功能的影响。方法 :用D -半乳糖衰老模型小鼠连续灌服复方三七口服液 2 0 ,40ml·kg- 1 /d× 64d ,分别测定免疫和抗氧化功能。结果 :复方三七口服液能增加D -半乳糖实验性衰老模型小鼠脏器指数 ,加快碳粒廓清速率 ,增强淋巴细胞转化能力 ,明显提高血清超氧化物歧化酶水平并降低脂质过氧化物含量。结论Objective:To investigate the effect of Compound sanqi oral liqour(CoSQ) on immune and anti-oxidation of aging mice.Methods:CoSQ was administrated 20,40ml/kg per day for 64 days to experimental models aged mice induced by D-galactose,then the Immune and antioxidant functions were estimated.Results:CoSQ Could obviously increase the organ index,carbon granule clearance and promote the speen lymphocyte proliferation and increased the activity of superoxide dismutase(SOD) in serum,in addition,CoSQ could obviously decreas the content of malondialdehyde(MDA) in serum of aged mice.Conclusion:CoSQ could delay aging induced by D-galactose in mice by enhancing immune function and anti-oxidation function.

关 键 词：复方三七口服液 碳粒廓清 淋巴细胞转化 超氧化物歧化酶丙二醛 中药 药理 

分 类 号：R285.5[医药卫生—中药学]