糖尿病自主神经病变的心率变异性分析  

Heart rate variability analysis to diabetic autonomic neuropathy

作　　者：李永勤[1] 耿琪 高方[3] 邓亲恺[1] 

机构地区：[1]第一军医大学生物医学工程系医学物理教研室,广东广州510515 [2]解放军323医院器械科,陕西西安710054 [3]第一军医大学附属南方医院内分泌科,广东广州510515

出　　处：《中国医学物理学杂志》2003年第1期49-52,共4页Chinese Journal of Medical Physics

基　　金：广东省重点科技攻关项目(99M04701G)

摘　　要：糖尿病病人神经病变发病率高达60％～90％,尤其是自主神经病变,是致残、致死的重要原因。本研究采用基于LabVIEW的虚拟仪器开发平台,对糖尿病患者自主神经病变的各心率变异性(HRV)指标与正常人群进行了量化对比,并对各指标的相关性与有效性进行了分析对比。结果表明:无论糖尿病患者是否并发自主神经病变,用HRV分析的方法均可以得到有关自主神经系统功能变化的状态信息。我们认为,以先进的虚拟医学仪器开发系统为手段,将HRV非线性动力学分析方法与时频域分析相结合,将HRV分析方法与其它检测方法相结合,是提高自主神经病变的早期诊断率的有效途径。Neuropathy rate of DM patients is about 60%-90%, especially Diabetic Autonomic Neuropathy (DAN), is the main cause of disabled and death. This research is based on Virtual Instrumental WorkBench-LabVIEW, using several different measures to compare these quantitative indices between normal subjects and DM patients. This article also compares the validity and correlation among these quantitative indices. Our research confirms that HRV analysis can get the information about Autonomic Nerve dysfunction. We think that considering the whole nerve system, combing these quantitative indices with other DAN earlier detecting methods is an efficient way to detect the onset of Diabetic Neuropathy.

关 键 词：糖尿病 自主神经病变 HRV分析 

分 类 号：R587.2[医药卫生—内分泌] R331.38[医药卫生—内科学]