胸血自体回输后患者体内抗心肌抗体的检测  

Detection of anti cardiac muscle antibody in the patients after autotransfusion of hemothorax blood

作　　者：吴昊[1] 李钰[1] 王奇[1] 

机构地区：[1]广西医科大学第四附属医院,柳州545005

出　　处：《上海医学检验杂志》2003年第1期26-27,共2页Shanghai Journal of Medical Laboratory Sciences

摘　　要：目的　了解胸血自体回输后患者抗心肌抗体 (anticardiacmuscleantibody ,ACMA)的产生情况 ,为临床自体血回输工作的开展提供科学依据。方法　用ELISA法检测血清中的ACMA ,设心胸创伤或心脏手术患者实施自体血回输的实验组 ,与心胸创伤未进行自体血回输对照组及正常人对照组进行对照。结果　实验组的ACMA检出率是 11.4 3% ,心胸创伤未进行自体血回输组的ACMA检出率是 9.76 % ,两组结果的差异无显著性(χ2 =0 .0 5 6 ,0 .5 0 0 >P >0 .2 5 0 ) ,但这两组的检出率均明显高于正常人对照组 (0 % ,χ2 值和P值分别是 χ2 =7.85 4 ,0 .0 10 >P >0 .0 0 5和 χ2 =6 .6 89,0 .0 10 >P >0 .0 0 5 )。Objective To detect anti cardiac muscle antibody(ACMA) in the patients after autotransfusion of hemothorax blood and to find out if it is safe to use hemothorax blood for autotransfusion. Methods Using ELISA kit to test ACMA of the test group and control groups. Results The positive rates of ACMA were 11.43% in the test group and 9.76% in the control group in which the heart\|injured patients had not used autotransfusion from hemothorax. The difference of the result between these two groups is not remarkable( χ 2=0.056, 0.500> P >0.250). None of the control group of healthy persons is positive. Conclusion Autotransfusion from hemothorax blood does not increase the rish of producing ACMA.

关 键 词：抗心肌抗体 自体血回输 自身免疫 检测 

分 类 号：R446.62[医药卫生—诊断学]