Acute and chronic effects of tributyltin on Chinese rare minnow（Gobicypris rarus）  

作　　者：ZhouQF LiZY 

机构地区：[1]ResearchCerterforEco－EnvironmentalSciences,ChineseAcademyofSciences,Beijing100085,China [2]DepartmentofChemistry,KeyLaboratoryofEnvironmentalScienceandEngineering,Xinxiang453002,China

出　　处：《中国药理学与毒理学杂志》2002年第6期418-419,共2页Chinese Journal of Pharmacology and Toxicology

摘　　要：The acute(12-h) and chronic (7 or 14-4) effects of tributyltin chloride(TBT) on a new type of test fish-Chinese rare minnow(Gobiocypris rarus) were studied.High accumulations of the pollutant in the fish muscle were observed after exposure.In chronic exposed group,hepatosomatic index and gonad somatic index occurred obvious changes.The ultrastructural findings showed a series of pathological changes such as the fractured or distorted nuclear,fomation of self-devouring bubble,many vacuoles existing in the exposed gill cells or hepatocytes,which demonstrated the toxic effects of tributyltin compounds on aquatic organisms.The results clearly showed that Chinese rare minnow was a new sensitive test fish,whose exposed system was suitable for the extensive organometallic toxicity studies.

关 键 词：中国 Shun鱼 三丁基锡 有机金属毒性 实验动物 检查 

分 类 号：R99[医药卫生—毒理学]