异丙酚用于烧伤患儿静脉麻醉的临床观察  

Ginical study of propofol in total intravenous anesthesia of burnt children.

作　　者：曾宪阳[1] 刘纪泽[1] 于长泉 袁秀英[1] 唐闽[1] 

机构地区：[1]武警辽宁总队医院麻醉科,沈阳110034

出　　处：《武警医学》2003年第1期27-29,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的 比较烧伤患儿静脉麻醉(Total intravenous anesthesia,TIVA)中异丙酚、氯胺酮、咪唑安定、芬太尼之间的麻醉效应。方法 患者60例,随机分成两组。实验组给予异丙酚2～8mg/(kg·h),氯胺酮1～4mg/(kg·h);对照组给予氯胺酮1～4mg/(kg·h),γ-OH 20～60mg/kg,静脉滴注。两组适时应用咪唑安定0.03～0.1mg/kg、芬太尼0.8～1.6μg/kg。结果 两组麻醉后比较,SBP、DBP、HR、VT、SpO_2之间差异有极显著性意义(P<0.01)。结论 异丙酚复合用于烧伤患儿TIVA,具有心血管系统平稳、呼吸抑制轻微、药物之间副作用少、术中及术后并发症少等优点。Objective To study and compare the effects of propofol, ketamine, midazolam, fentanyl in total intravenous anesthesia of burnt children.Methods Sixty patients, ASA gradesⅠ and Ⅱ , were randomly allocated to two groups: experimental group (group P, n = 30) was given propofol 2 - 8 mg/kg ivd and ketamine 1 - 4 mg/kg ivd in an hour;contrast group (group K, n = 30 ) was given ketamine 1 - 4 mg/kg ivd in an hour and γ- OH 20-60 mg/kg iv were used. Midazolam 0.03 - 0.1 mg/kg iv were used p.r.n. and fentany 0.8 - 1. 6μg/kg iv in two groups. Results Compared between the two groups, the differences in SBP,DBP,HR,RR and VT,Sp02 were significant ( P <0.01), while that in RR ( P > 0.05). Conclusions In group P, circulatory system keeps stable and respiratory inhibition is slight during anesthesia induction, side reactions between drug are reduced during period of anesthesia, and there are few complications during and after operation.

关 键 词：异丙酚 烧伤 静脉麻醉 儿童 TIVA 

分 类 号：R644[医药卫生—外科学] R614.24[医药卫生—临床医学]