糖尿病酮症酸中毒致多器官功能衰竭的分析  

Diabetic Ketoacidosis Resuting in Multiple Organic Failure

作　　者：李进[1] 王淑娟[1] 吴爱英[1] 

机构地区：[1]山东省淄博市中心医院内科,山东淄博255036

出　　处：《中国医师杂志》2003年第1期51-53,共3页Journal of Chinese Physician

摘　　要：目的　通过对糖尿病酮症中毒 (DKA)合并多器官功能衰竭 (MOF)的诱因和临床表现等进行分析 ,以提高DKA合并MOF的认识 ,及时防治。方法　采用病例回顾分析的方法 ,对我院 1997～ 2 0 0 0年 4年间收治的 5 3 7例糖尿病患者的临床资料进行总结 ,特别分析 182例DKA及其中的DKA合并MOF的患者。DKA合并MOF的诱因、临床表现、MOF的器官受累情况及转归进行总结分析。结果　分析表明DKA合并MOF的主要诱因为感染 (占 84 5 % ) ,高龄患者 (大于 60岁 )易发生MOF。MOF的主要受累器官依次为肾脏、心脏和脑等 ,MOF受累的器官数目与死亡率密切相关。结论　防治感染是减少DKA合并MOF的可能途径 ,DKA患者密切注意肾、心和脑等器官的损害 ,以防MOF。Objectives To analyse the predisposing cause and clinical manifestasion of diabetic ketoacidosis (DKA) complicated with multiple organic failure (MOF),in order to diagnose early and management timely.Methods 537 diabetic patients admitted in our hospital from 1997 to 2000 were included in this cases retrospective study. 182 cases of them complicated with DKA or DKA complicated with MOF (58) were further analyzed by cause, clinical manifestation, number of organs in MOF and the prognosis. Results Analysis showed that the main cause of MOF in DKA patients was infection (84 5%). The higher incidence of MOF in older DKA patients than those of younger. The possible involved organs in MOF were kidney, heart and brain etc. Involving organs of MOF were much, the mortality was closely correlated with the number of involved organs. Conclusions The possible way to reduce the incidence of MOF in DKA patients is intensive preventing and treating infection. To avoid MOF occurring in DKA patients, complications of kidney, heart and brain should be timely diagnosed and managed.

关 键 词：糖尿病酮症酸中毒 多器官功能衰竭 MOF DKA 临床表现 病例分析 

分 类 号：R587.2[医药卫生—内分泌] R59[医药卫生—内科学]