机构地区:[1]哈尔滨医科大学中国疾病预防控制中心地方病控制中心大骨节病防治研究所,黑龙江哈尔滨150001
出 处:《中国地方病学杂志》2002年第6期459-463,共5页Chinese Jouranl of Endemiology
基 金:卫生部疾控司支持项目 (2 0 0 10 12 5
摘 要:目的 探讨中国成人骨关节炎手骨 X线检出水平的地理分布及其差异。方法 流行病学现场调查 ,涉及黑龙江、辽宁、河北、山东、河南、江苏、浙江、湖北、湖南、福建、广东、广西、海南、山西、陕西、甘肃、青海、四川、新疆等 19个省份 ;每个省选出 2~ 3个有代表性的村落 ,每个村找出 4 0岁以上人口 70~ 10 0人拍摄右手 X线片 ,共拍摄了 2 6 98张 ,按计分法给病变程度量化 ,用 Ridit法作统计分析。结果 以 Ridit指数及其 95 %可信限表示检出水平及其可靠程度 :1尚志、吉县、永寿、麟游、若尔盖等原大骨节病重病区成人骨关节炎最重 ,指数及其95 %可信限分别为 0 .83,0 .81~ 0 .86 ,为全国之最 ;2贵德、张家川等原大骨节病较轻病区 ,相应数值为 0 .5 5 ,0 .5 0~ 0 .6 0 ;3哈尔滨及其郊区、吉县雷家、宝鸡金台、青海湟中、哈密等北方面食的非病区再次之 ,为 0 .4 7,0 .4 5~0 .5 0 ;4苏家屯、淄博、张掖、酒泉、保定、黄骅、新郑、咸宁、会同、桂林、三亚、惠东、漳州等广大地区又次之 ,为 0 .4 1,0 .39~ 0 .4 2 ,代表中国成人骨关节炎患病程度的基本水平 ;5扬州、绍兴、郫县等大米占主食绝大部分的水田区病情最低 ,为 0 .36 ,0 .39~ 0 .4 0。差别明显 ,呈规律的梯度。结论 中国中老年骨关节炎的右?Objective To discover the characters of the geographic distribution of adult osteoarthritis {OA} prevalence in China.Methods Epidemiologic studies on a wide region, including 19 provinces, such as Heilongjiang, Liaoning, Hebei, Shandong, Henan, Jiangsu, Zhejiang, Hubei, Hunan, Fujian, Guangdong, Guangxi, Hainan, Shansi, Shanxi, Gansu, Qinghai, Sichuan, Xinjiang et al. From each province 2~3 villages were selected as the typical points for studies, and 70~100 adults aged over 40 years were sampled from each village and tested their right hand, by a radiography. All films were read by a specialist in Kaschin Beck disease studies and keeps a score relevant to the seriousness of the situation of OA for each one .The results were expressed and analyzed by a statistic analysis named as Ridit index including the estimated 95% confidence interval.Results The Ridit index of adult OA in areas of different geographic type showed significant differences in numerical value, the highest one is 0.83 and the lowest one is 0.33. In former serious KBD areas the Ridit index of adult OA is high (0.83, 0.81~0.86); in some low prevalence areas of KBD the Ridit index of adult OA is also lower(0.55, 0.50~0.60); in areas near the KBD area and some cold north region, the OA Ridit index posed the third position in order, it is (0.47, 0.45~0.50); the fourth of the Ridit indexes is (0.41, 0.39~0.42), and it is the most popular condition covered a wide region except KBD areas in our country; the fifth in order of the Ridit indexes in the whole country is (0.36, 0.33~0.4), and it is the lowest and found only in districts growing rice and the people living there uses rice as staple food only.Conclusions The characters shown the geographical distribution of the adult OA prevalence suggested that the cause and factors related to it may be affected and conditioned strongly by the natural and social environment. In future we must pay more attention to geographic factors for prevention and studies of the disease.
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