新生儿出生季节对脐带血TSH值影响分析  

Impact of different birth seasons of neonate on the TSH of cord blood

作　　者：郑朝晖 龚新国 陈连璋 陆剑波 阎文汉 

机构地区：[1]湖北省卫生防疫站,湖北武汉430079 [2]宜昌市卫生防疫站,湖北宜昌443000 [3]咸宁市卫生防疫站,湖北咸宁437100 [4]随州市卫生防疫站,湖北随州441300

出　　处：《中国地方病学杂志》2002年第6期470-472,共3页Chinese Jouranl of Endemiology

摘　　要：目的　探讨新生儿出生季节对碘营养状况正常的新生儿脐带血促甲状腺激素 (TSH)水平的影响 ,为建立适合我国国情的新生儿 TSH正常值范围提供依据。方法　在湖北省碘营养状况良好的 3个市区 ,历时 1年采集新生儿脐带血 6 4 9份 ,使用酶联免疫吸附法 (EL ISA)测定 TSH值。结果　新生儿 TSH中位数 3.4 4 6 m U/L,97%分位值为 11.96 4 m U/ L,>5 m U/ L 的比例为 2 5 .4 % ,且春、夏、秋、冬 4个季节之间差异有显著性意义。结论　在碘营养状况良好的环境下 ,新生儿出生季节是影响脐带血Objective To explore the impact of different birth seasons of neonate on TSH level of cord blood at good condition of iodine nutrition, and to supply with scientific evidence for establishing a normal value scope of neonatal TSH suitable for our country.Methods Six hundred and forty nine specimens of neonatal cord blood born from January through December are collected in three cities of Hubei, and detected with ELISA.Results The median of neonatal TSH is 3.415 mU/L, P97 is 11.964 mU/L, and 25.4% of neonatal TSH is more than 5 mU/L.P97 of TSH varies with different seasons, and the differences are very significant.Conclusions Birth season is one of the factors affecting TSH of neonatal cord blood at good condition of iodine nutrition.

关 键 词：促甲状腺激素 新生儿 脐带血 TSH值 碘营养 碘缺乏病 

分 类 号：R599[医药卫生—内科学]