^(169)Er-FHMA的制备  

The Preparation of ^(169)Er-FHMA

作　　者：刘中林[1] 

机构地区：[1]中国工程物理研究院核物理与化学研究所,四川绵阳621900

出　　处：《同位素》2002年第4期204-206,共3页Journal of Isotopes

摘　　要：利用天然丰度Er2O3(光谱纯)作靶料,经反应堆辐照后,用HNO3溶解生成169Er(NO3)3。在0.9%NaCl介质中,加入FeSO4、NaOH和稳定剂PVP(聚乙烯吡咯烷酮)经超声波分散,获得69Er-FHMA(氢氧化铁聚合体),用莱之超显微镜观察测定其粒径为3～8μm,实验表明169Er-FHMA在0.9%NaCl溶液中溶出率基本不受温度影响。The natural abundance Er2O3 is taken as the target,irradiated by reactor,and generated 169Er(NO3)3 solved in HNO3. In the medium of 0.9% NaCl,FeSO4,NaOH and the stable reagent of PVP is added while be keeping the definite acidity. The 169ErFHMA(Fe(OH)3 polymer) is gained after the dispersal by supersonic. The size of particles is 3～8 μm, the temprature is no effect on dissolve rate of 19ErFHMA in 0.9% NaCl solution.

关 键 词：^169Er-FHMA 放射性药物 制备 骨关节疾病 治疗 铒169 放射性同位素 标记 

分 类 号：R817.58[医药卫生—影像医学与核医学]