吸食阿片类毒品对T淋巴细胞亚群的影响及与中医肾虚相关关系的研究  

Influences of The T Lymphocyte Subgroups between the Health and Narcotic People

作　　者：郭瑞林[1] 赵宁侠[1] 任秦有[1] 周建歧 史恒军[1] 侯颖[1] 

机构地区：[1]第四军医大学唐都医院,西安710038 [2]西安市公安局灞桥公安分局戒毒所

出　　处：《浙江中医学院学报》2003年第1期26-27,共2页Journal of Zhejiang College of Traditional Chinese Medicine

摘　　要：目的 :研究吸食阿片类毒品对T淋巴细胞亚群影响及与中医肾阳虚相关关系的研究。方法 :测定外周血T淋巴细胞亚群以反映细胞免疫功能 ,进行戒断肾阳虚损症状积分评定。结果 :17例吸毒者外周血检测后T4(CD4+ )及T8(CD8+ )细胞百分率均较健康人低 ,尤以T4(CD4+)最为显著。T8(CD8+)细胞百分率依吸毒的时间 ,日吸入量及个体之间都有很大差异 ,17例都有典型肾阳虚损症状。结论 :吸毒者T淋巴细胞亚群功能低下 ,肾阳虚损明显 ,认定吸毒人员的中医证型是以肾阳虚损为主。Aim:To study the influence of T lymphocyte subgroups on narcotic people.Methods:The T lymphocyte subgroups of peripheral blood(including CD 4+ and CD 8+ )were measured by direct microvolume whole blood immunoflurescent staining technique with flowcytometer(FCM)in narcotic people.Results:The value of CD 4+ in narcotic people was significantly lower than that in normal people(P<0.01);CD 8+ was higher than that in normal people,but it was no significant difference from normal people(P>0.05).Conclusion:The narcotic people's Tlymphocyte subgroups of peripheral blood was lower than that in normal people.

关 键 词：吸毒者 T淋巴细胞亚群 肾阳虚损 阿片类毒品 吸食 相关关系 研究 

分 类 号：R595.5[医药卫生—内科学]