沙漠环境行军者谷胱甘肽含量和超氧化物歧化酶活性的变化  

Changes of glutathione (GSH) contents and superoxide dismutase (SOD) activity in marchers by stress marching in desert environment

作　　者：冯建江[1] 刘兵[1] 徐文[1] 张雪龄[1] 吴志豪[1] 邬堂春[2] 陈胜[2] 

机构地区：[1]兰州军区联勤部军事医学研究所,甘肃兰州730020 [2]华中理工大学同济医科大学职工医学研究所,430030

出　　处：《中国职业医学》2003年第1期35-37,共3页China Occupational Medicine

摘　　要：目的探讨沙漠环境应激行军负荷对行军者谷胱甘肽(GSH)含量和超氧化物歧化酶(SOD)活性的影响。方法 用化学比色法测定在沙漠干热环境中以不同速度和时间徒手和负荷行军的128名男战士血浆GSH含量和SOD活性,并进行比较分析。结果3.5 km/h和5.0 km/h速度徒手行军者CSH的变化规律完全不同,呈相反“S”状。3.5 km/h和5.0 km/h速度负重行军者GSH在应激的最初1 h内迅速上升,约1h时达到最高峰,之后迅速下降。徒手应激行军组SOD随行军时间的变化曲线均呈反“S”形。3.5 km/h速度15 kg负重行军的最初1 h内SOD迅速上升;5.0 km/h速度15kg负重行军的最初1 h内SOD缓慢上升,1 h后上升速度加快。结论沙漠应激行军者GSH含量和SOD活性的变化可能与应激行军有关。Objective To explore effects on glutathione (GSH) content and superoxide dismutase (SOD) activity of marchers by stress marching in desert environment. Methods Plasma GSH and SOD of 128 soldiers for different time at different speed, with or without load were detected in desert environment. Results Without load, the GSH curve in marchers at speed of 3.5 km/h was different from that at speed of 5.0 km/h, the former looked like 'S' shape, while the latter appeared in opposite direction of 'S . With 15 kg loading, the synthesis and consumption of GSH increased rapidly within the first hour, then dropped quickly; as for SOD, at speed of 3.5 km/h, increased rapidly in the first hour, then nearly kept steady at speed of 3.5 km/h, but at speed of 5.0 km/h, increased slowly in the first hour, then increased rapidly. Conclusion It suggested that changes of GSH content and SOD activity in marchers in desert environment might associate with stress marching.

关 键 词：沙漠环境 谷胱甘肽 超氧化物歧化酶 应激行军 

分 类 号：R821.52[医药卫生—临床医学] R135