静注丙球佐治毛细支气管炎47例  

Intraveneous immunoglobulin for the treatment of bronchiolitis 47 cases

作　　者：战永才 王宪华 王萍 于美平 

机构地区：[1]山东龙口市人民医院儿科,山东龙口265701

出　　处：《儿科药学杂志》2003年第1期51-52,共2页Journal of Pediatric Pharmacy

摘　　要：目的:评估静脉注射丙种球蛋白(IVIG)治疗毛细支气管炎的疗效。方法:比较47例IVIG治疗组和47例对照组症状、体征消失时间及住院天数,同时检测治疗前后的血清IgG、IgA、IgM的水平。结果:IVIG治疗组喘憋和肺部体征消失时间较对照组明显缩短(P均<0.01),住院天数无显著差异(P>0.05);治疗组的血清IgG明显高于对照组(P<0.001)。结论:IVIG对于治疗毛细支气管炎有良好疗效。Objective: To evaluate clinical effect of intraveneous immunogobulin (IVIG) treatment of bronchiolitis. Methods: The recovery time of clinical signs and symptoms and durations of hospitalization were compared between the IVIG group and the conventional group. The level of serum Ig were determined before and after IVIG therapy in treatment group. Results: The result showed that the level of IgG was higher in the IVIG group compared with the comventional group ( P < 0. 001) . The recovery time of clinical wheezing and lung signs were obviously shortened in the IVIG group compared with the conventional group ( P < 0. 01). No significant difference of hospitalization days was observed in two groups ( P > 0. 05). Conclusions: IVIG treatment of bronchiolitis had better clinical effect.

关 键 词：毛细支气管炎 免疫球蛋白 静脉注射 

分 类 号：R979.5[医药卫生—药品] R725.6[医药卫生—药学]