磁共振灌注成像对高级胶质瘤、转移瘤及脑脓肿的鉴别诊断价值  

A Study of the Differential Diagnostic Potential of Perfusion MR Imaging among High-Grade Gliomas,Metastatic Tumor and Abscess of Brain

作　　者：钱银锋[1] 余永强[1] 郑斐群[1] 张诚[1] 柏亚[1] 陈骏[1] 

机构地区：[1]安徽医科大学第一附属医院放射科,安徽合肥230022

出　　处：《中国医学影像技术》2003年第2期149-151,共3页Chinese Journal of Medical Imaging Technology

基　　金：安徽省自然科学基金资助 (990 4 4 530 )

摘　　要：目的　评价磁共振灌注加权成像 (PWI)对Ⅲ～Ⅳ级胶质瘤、脑转移瘤及脑脓肿的诊断和鉴别诊断价值。方法　本组 3 1例病人行PWI ,绘制出灶周区和对侧对称区的信号强度 时间曲线 ,计算两兴趣区最大信号强度下降百分比、相对脑血流容积 (rCBV)之比值Q。并计算病变自身的rCBV。结果　Ⅲ～Ⅳ级胶质瘤、脑转移瘤和脑脓肿的QSRR分别为 1.88、0 .3 1、0 .95 ,QrCBV为 2 .61、0 .2 6、1.0 1,各组Q值间具有显著统计学差异 ,而病变的灌注间则无统计学差异。结论　PWI在Ⅲ～Ⅳ级胶质瘤、脑转移瘤及脑脓肿的诊断和鉴别诊断中具有重要价值。Objective To evaluate the potential of perfusion weighted imaging (PWI) in diagnosis and differential diagnosis among malignant glioma,metastatic tumor and abscess of brain. Methods PWI was performed in 31 patients to get signal intensity percentage time curves of perilesion and contralarteral symmetric region,which were used to calculate maximum signal reduction ratio (SRRmax) and relative cerebrum blood volume (rCBV). The ratio Q of SRRmax and rCBV in both ROIs was calculated. In addition,SRRmax and rCBV of the lesions were calculated. Results The Q SRR values were 1.88,0.31 and 0.95 in grade Ⅲ-Ⅳ gliomas,while Q rCBV values in metastatic tumors and brain abscess were 2.61,0.26 and 1.01 respectively. The difference in the Q values was statistically significant among three groups,and the values of lesions had no obvious discrepancy. Conclusion PWI is very useful in diagnosis and differential diagnosis among grade Ⅲ-Ⅳ gliomas,metastatic tumors and abscess of brain.

关 键 词：胶质瘤 转移瘤 脑脓肿 磁共振灌注加权成像 鉴别诊断 统计学 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]