2型糖尿病检测晨尿Alb的临床价值  

The Clinical Significance of Detection of Urinary Albumin in Type2Diabetes

作　　者：赵春荣[1] 陈高翔[1] 桂树华[1] 邹新中[1] 

机构地区：[1]南通医学院附属第三人民医院内科,江苏无锡214041

出　　处：《中国微循环》2003年第1期46-47,共2页Journal of Chinese Microcirculation

摘　　要：目的评价测定2型糖尿病患者晨尿白蛋白(Alb)的临床价值。方法同期检测20例正常人和33例2型糖尿病患者晨尿Alb/Cr比值、Alb和α1-微球蛋白(α1-MG)浓度。结果(1)Alb/Cr≥2.5mg/mmol为早期糖尿病肾病诊断标准 ,早期糖尿病肾病组晨尿Alb较糖尿病尿白蛋白正常组显著升高 (P<0.001) ,亦较正常人显著升高(P<0.001)。(2)晨尿Alb和尿Alb/Cr在正常人或2型糖尿病人中 ,均呈正相关。结论晨尿Alb可作为监测2型糖尿病肾脏早期病变指标之一。Objective To evaluate the clinical significance of detection of urinary albumin in type2diabetes.Methods To measure albumin/creatimine(Alb/Cr)and urinary albumin andα 1 _microglobulin(α 1 _MG)in morning urinary specimens,from20normal controls and33diabetes.Results(1)Urinary Alb/Cr≥2.5mg/mmol was considered as a marker of diabetes nephropathy(DN).Urinary was significantly increased in DNthan that in diabetes with normal urinary Alb.(2)Urinary Alb and Alb/Cr was positively correlated in controls and type2diabetes.Conclusions Urinary Alb could be considered a marker of inspection in DN.

关 键 词：2型糖尿病 糖尿病肾脏病变 晨尿白蛋白 

分 类 号：R587.1[医药卫生—内分泌]