HLA基因多态性及其法医学应用  

HLA gene polymorphism and forensic medicine

作　　者：靳大庆[1] 郑秀芬[1] 

机构地区：[1]中国人民公安大学研究生部,北京100038

出　　处：《法医学杂志》2003年第1期51-53,共3页Journal of Forensic Medicine

基　　金：国家自然科学基金资助项目(No.30070831)

摘　　要：人类白细胞抗原(Human Leukocyte Antigen,HLA)基因复合物定位于人类第6号染色体短臂上,是人类最复杂的显性多态遗传系统,基因型可达108种之多,是理想的人类遗传标记,已广泛应用于法医学亲子鉴定和个体识别。本文就其基因多态性的研究进展和在法医学中的应用作一综述。The gene complex of Human Leukocyte Antigen (HLA) is located of chromosome 6p21, which is the most complicated dominant polymorphic genetic system. The HLA system has 108 genotypes. It is the best human genetic marker. It has been applied to forensic paternity test and individual identification. This article discusses the research development of HLA polymorphism and its application in forensic medicine.

关 键 词：HLA基因 多态性 法医学 

分 类 号：D919.6[医药卫生—法医学]