血清胆固醇酯转运蛋白测定的临床应用  

Clinical application of measurement of serum cholesteryl ester transfer protein

作　　者：胡汉宁[1] 陈薇[1] 杨桂[1] 贺小玲[1] 吴翠华[1] 

机构地区：[1]武汉大学中南医院检验科,430071

出　　处：《重庆医学》2003年第3期301-302,共2页Chongqing medicine

摘　　要：目的　了解血清胆固醇酯转运蛋白 (CETP)对动脉粥样硬化的致病关联性。方法　以ELISA法检测血清中CETP的浓度 ,同时检测了血脂其他相关指标。进行统计学处理 ,进行正态性检验 ,相关分析 ,参考值的确定。结果　正态性检验呈正偏态分布。参考范围 0 .33～ 4 .7mg L。CETP与脂类其它指标无明显的相关性。结论　显示CETP浓度过高或过低或缺乏均与动脉粥样硬化的形成存在着明显的关联性 。Objective To understand the relation between serum cholesteryl ester transfer protein(CETP),concentration and atherosclerosis(AS) pathogenesis.Methods Serum CETP concentration and other blood lipid correlated indexes were measured,simultaneously,by ELISA method,statistical analysis,normality test,correlation analysis and determination of reference value were done.Results The normality test shows positive partial distribution,the reference interval is 0.33～4.7 mg/L,There is no significant correlation between serum CETP concentration and other blood lipid indexes.Conclusion There is a significant correlation between the formation of atherosclerosis plaques and the increase or decrease of serum CETP concentration or its deficiency. It has a great clinical value.

关 键 词：胆同醇酯转运蛋白 分析 动脉粥样硬化 

分 类 号：R446.61[医药卫生—诊断学]