造影剂超声图像的纹理与心腔内压力相关性研究  

On the Correlation between the Texture of Contrast Agent Ultrasonic Image and the Intracardiac Pressure

作　　者：林江莉[1] 汪天富[1] 李德玉[1] 尹光福[1] 尹立雪[2] 郑昌琼[1] 郑翊 

机构地区：[1]四川大学生物医学工程系,成都610065 [2]四川省人民医院彩色超声诊断室,成都610072 [3]Department of Electrical Engineering,St.Cloud State University,St.Cloud,MN 56301,USA

出　　处：《生物医学工程学杂志》2003年第1期52-55,共4页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助课题 ( 60 172 0 5 9;69972 0 2 9)

摘　　要：用计盒分形模型分析经静脉注射 L evovist声学造影剂后在二次谐波成像方式下的超声图像纹理变化 ,研究发现左心室区域超声图像的分形维数 D和分形辅助特征量 C( L)在连续心动周期中具有规律性变化。即分形维数 D的最大值出现在舒张末期 ,最小值出现在收缩末期 ,随着心室收缩期开始 ,D值由大变小 ,而舒张期开始 ,D值又由小变大 ;而分形辅助特征量 C( L)的最大值出现在收缩末期附近 ,最小值出现在舒张末期附近 ;从左室收缩期开始到收缩末期之间 C( L)具有由小变大的趋势 ,舒张期开始到舒张末期之间具有由大变小的趋势。它们的这种变化与左心室内压力的变化情况十分相似 ,可见造影剂超声图像的分形纹理特征与心腔内压力的变化具有相关性。Base on the application of box-counting fractal model to the textrue analysis of ultrasonic image after intravenous injection of Levovist acoustics contrast agent in a dog, a method to calculate the fractal dimension(D) and assistant characteristic(C(L)) of the ultrasonic images of left ventricle is presented. It is found that the D and C(L) changed regularly in the continued cardiac cycles, that is, the maximum value of D appears during diastasis, and the minimum value appears during end-systole; as the ventricular systole begins, D changes from maximum to smallness, and as the diastole begins, D changes from smallness to maximum; the maximum value of C(L) appears around end-systole, and the minimum value appears around diastasis; from the start of left ventricular systole to end-systole, C(l) shows a tendency to change from smallness to maximum, and from the start of diastole to diastasis, it shows a tendency to change from maximum to smallness. The changes of D and C(L) are very similar to the changes of left ventricular pressure. It is thus evident that there is correlation between the fractal texture characteristics of the contrast agent ultrasonic images and changes of intracardiac pressure. The results demonstrate that it is possible to measure the intracardiac pressure noninvasively.

关 键 词：心腔内压力 声学造影剂 分形模型 纹理分析 超声图像 

分 类 号：R310[医药卫生—基础医学]