电解铝厂接触多环芳烃的生物监测指标——1-羟基芘的研究  

STUDY ON BIOLOGICAL MONITORING INDEX (1-HYDROXYPYRENE)FOR WORKERS EXPOSED TO PAH IN ELECTROLYTICALUMINIUM PRODUCTION

作　　者：线引林[1] 李晓华[1] 王敢峰[1] 曲正和[2] 郝如军 韩辉[2] 隋锡伦 胡玉良 

机构地区：[1]中国预防医学科学院劳动卫生与职业病研究所,北京市宣武区南纬路29第100050 [2]本溪钢铁公司劳动卫生研究所 [3]本溪钢铁公司焦化厂 [4]抚顺铝厂职工医院

出　　处：《工业卫生与职业病》1992年第5期257-260,共4页Industrial Health and Occupational Diseases

摘　　要：芘是多环芳烃的一个代表性化合物。预防职业性癌症将测定尿中芘的主要代谢物1-羟基芘作为接触多环芳烃的生物监测指标。对不同工作岗位的电解铝工人,同时测定个体接触多环芳烃的浓度及尿中排出1-羟基芘的浓度,发现在个体评价的基础上,1-羟基芘的水平与空气中芘的浓度、与空气中苯并(a)芘的浓度都呈显著相关,与空气中多环芳烃总浓度也呈显著相关。Pyrene is a representative compound among PAH.In the prevention of occupational cancer.1-Hydroxypyrene,the main metabolite of PAH in urine,was taken as a biological monitoring index for workers exposed to PAH. Personal exposure level of PAH in air and the concentration of 1-hydroxypyrene in urine were determined simultaneously in electrolytic aluminium workers of different worposts.Results showed that, on the basis of personal evaluation, significant correlationships existed between 1-hydroxypyrene level and airborne pyrene concentration, and benz (a) pyrene concentration in air. There was also significant correlationship between 1-hydroxypyrene in urine and total PAH concentration in air.

关 键 词：1-羟基芘 多环芳烃 电解铝厂 

分 类 号：R134.4[医药卫生—劳动卫生]