自动电位滴定法测定慢性肾脏病患者尿液的临床意义  

Detection of Urine from Patients with Chronic Renal Desease by TITRATOR(ZD-2)

作　　者：蒋红樱[1] 石红[1] 杨敏[1] 赵劲涛[1] 

机构地区：[1]昆明医学院第二附属医院肾内科,昆明650101

出　　处：《昆明医学院学报》2003年第1期74-76,共3页Journal of Kunming Medical College

摘　　要：目的 :通过测定尿液碳酸氢根、可滴定酸和铵离子的含量 ,以了解和研究肾脏调节酸平衡的功能 .方法 :运用ZD - 2型自动电位滴定仪测定正常人 136例及慢性肾脏疾病患者 4 2 5例尿中pH值、碳酸氢根(HCO-3 )、可滴定酸 (TA)、铵的含量 .结果 :肾功能正常组半数以上病例肾小管功能异常 .肾功能异常组尿HCO-3 ,TA ,NH+ 4 的排泻量显著低于对照组 (P <0 0 1) .结论 :尿酸化功能检测简单方便 。Objective: To understand and study the renal adjustment function of the acidbase balance status by testing the content of bicarbonate, titratable acid (TA) and ammonium in the urine. Methods: To test the pH, HCO - 3, TA and NH + 4 in the urine of 136 normal person cases and 425 chronic renal disease patient cases by the TITRATOR(ZD-2). Results: More than half of normal person cases showed the abnormal function of renal tubules and the excretion of HCO - 3, TA and NH + 4 in the urine of the patients case group was significant lower than the cross-reference group (P<0 01). Conclusion:The urine acidification function test is a simple and convenient way, which is a sensitive indicator in the observation of the tubulointerstitial injury.

关 键 词：肾脏疾病 肾小管功能 自动电位滴定法 

分 类 号：R692.04[医药卫生—泌尿科学]