人细小病毒B19与自然流产关系的研究  

Study on the relationship between human parvovirus B19 and the spontaneous abortion by polymerase chain reaction

作　　者：谭继英[1] 高峻[2] 兰中芬[1] 

机构地区：[1]兰州医学院病原生物学教研室,兰州730000 [2]兰州医学院第二附属医院妇产科

出　　处：《微生物学免疫学进展》2003年第1期5-6,共2页Progress In Microbiology and Immunology

基　　金：甘肃省教育厅科研项目 (项目编号 :986 2 4)

摘　　要：无菌留取 5 4例自然流产妇女和 43例妊娠无异常孕妇血清 ,用聚合酶链反应 (PolymeraseChainReaction ,PCR)检测的人细小病毒B19(HumanParvovirusB19,B19)DNA ,在自然流产组中人细小病毒B19DNA有 15例阳性 ,阳性率为 2 7.78%。正常对照组中 ,人细小病毒B19DNA有 2例为阳性 ,阳性率为 4.65 % ,用x2 检验 ,x2 =8.86,P <0 .0 1,两组有非常显著性差异。由此总结 。This study was on the relationship between human parvovirus B19 infection and spontaneous abortion.Human parvovirus B19 DNA was detected by polymerase chain reaction (PCR) in seruum samples from groups of spontaneous abortion (test group, n=54)and normal pregnant woman (control group,n=43).The positive rates of B19 DNA were 27.78%(15/54)in tested group and 4.63%(2/43)in control group, respectivelly. The difference was statistically significant (x 2=8.86,P<0.01)between the two groups.The results indicated that human parvovirus B19 infection may be associated with spontaneous abortion

关 键 词：自然流产 人细小病毒B19 聚合酶链反应 

分 类 号：R714.21[医药卫生—妇产科学]