乙型脑炎患儿脑脊液细胞因子含量检测的临床意义  

Clinical significance of detection of cytokines in cerebrospinal fluid(CSF) in children with encephalitis B

作　　者：何浩明[1] 田小平[1] 孙贵[2] 华岚[3] 丁丽[3] 刘忠伦[1] 

机构地区：[1]江苏省连云港市第一人民医院临床免疫室,江苏镇江212000 [2]江苏省连云港市第一人民医院儿科,江苏镇江212000 [3]江苏省连云港市第一人民医院镇江医学院,实习生江苏镇江212000

出　　处：《淮海医药》2003年第2期87-88,共2页Journal of Huaihai Medicine

摘　　要：目的　探讨乙型脑炎患儿脑脊液细胞因子含量的变化。方法　应用免疫化学法测定了 3 8例乙型脑炎患儿脑脊液中 IL - 6、IL - 8、TNF水平。结果　乙型脑炎患儿脑脊液中 IL - 6、IL - 8、TNF含量均高于正常儿 ( P<0 .0 0 1)。结论　细胞因子不仅具有抗病毒作用 。Objective To study the changes of cytokins in CSF in children with encephalitis B.Methods Thirty-eight patients with encephalitis B were tested with immunological chemistry methods for levels of CSF IL-6,IL-8?TNF.Results IL-6?IL-8?TNF levels in children with encephalitis B were higher than those in normal controls(P<0.001).Conclusion These cytokines not only have anti-viral effect,but also play a role in pathogenesis of encephalitis B in children.

关 键 词：乙型脑炎 脑脊液 检测 临床意义 白细胞介素-6 白细胞介素-6 肿瘤坏死因子 

分 类 号：R725.123.2[医药卫生—儿科]